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Anti-DENND1B Antibody (aa39-68) LS-C167360

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DENND1B Antibodies

Anti-DENND1B Antibody (aa108-157) IHC-plus™ LS-B5832
Rabbit Polyclonal (IgG) to Human DENND1B
Human, Bovine, Dog, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-DENND1B Antibody (aa144-193) IHC-plus™ LS-B5833
Rabbit Polyclonal (IgG) to Human DENND1B
Human, Monkey, Mouse, Bat, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-DENND1B Antibody (aa46-76, AP) LS-C234525
Rabbit Polyclonal (IgG) to Human DENND1B
Human
IHC, Western blot, Flow Cytometry, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human DENND1B
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated

Details

Human DENND1B
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

DENND1B antibody was raised against kLH-conjugated synthetic peptide between amino acids 39-68 from N-terminal region of human DENND1B.
aa39-68
Human DENND1B

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About DENND1B

Q6P3S1 NM_144977 NP_659414.2

DENND1B Antibody, C1ORF18 Antibody, C1orf218 Antibody, Connecdenn 2 Antibody, DENN/MADD domain containing 1B Antibody, Protein FAM31B Antibody, FAM31B Antibody, RP11-53I24.2 Antibody

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).

Immunohistochemistry

Immunohistochemistry
DENND1B antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lymph tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot
DENND1B Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The DENND1B antibody detected the DENND1B protein (arrow).

Flow Cytometry

Flow Cytometry
DENND1B Antibody flow cytometry of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
 

Requested From: United States
Date Requested: 12/4/2016

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