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Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles.
Gene Name: | DENN/MADD domain containing 1A |
Synonyms: | DENND1A, Connecdenn 1, Connecdenn, DENN/MADD domain containing 1A, FAM31A, KIAA1608, RP11-230L22.3, Protein FAM31A |
Target Sequences: | AB046828 BAB13434.2 Q8TEH3 |
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