Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone RFD1] (IgM) to Human Dendritic Cells
IHC - Frozen
Human Dendritic Cells
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [RFD1]
IHC - Frozen
IHC - Paraffin
Specificity and Use
Recognizes an epitope within the class II MHC complex. In normal tissueidentifies dendritic cells and a proportion of B lymphocytes. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is co-expressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation. Does not bind to monocytes or cells of the granulocyte lineage. Has been used for the induction of apoptosis via MHC Class II cross linking of gastric mucosa epithelial cells.
0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.