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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DEFA5 / Defensin 5 Antibody (clone 8C8, DY550) LS‑C141653
Defensin 5 antibody LS-C141653 is a DY550-conjugated mouse monoclonal antibody to human Defensin 5 (DEFA5). Validated for IF, IHC and WB.
Catalog
Size
Price
LS-C141653-100
100 µl
Unavailable

Popular DEFA5 / Defensin 5 Products

Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Rabbit
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3145 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot

Product Description

Defensin 5 antibody LS-C141653 is a DY550-conjugated mouse monoclonal antibody to human Defensin 5 (DEFA5). Validated for IF, IHC and WB.
About DEFA5 / Defensin 5
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. Q01523 NM_021010 NP_066290.1

DEFA5 Antibody, DEF5 Antibody, Defensin, alpha 5 Antibody, Defensin 5 Antibody, Defensin-5 Antibody, HD-5 Antibody, HD5(20-94) Antibody


Specifications

Target
Human DEFA5 / Defensin 5
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal [8C8]
Conjugations
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Purification
Purified IgG
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence (10 µg/ml)
  • Western blot (10 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Full-length proHD5 protein. [Swiss-Prot# Q01523] The propeptide is the full-length protein. In the mature form, it is cleaved at residue 63 (alanine)
Specificity
HD5. It does not cross-react with HD6, lysozyme or sPLA2.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2904 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/19/2018

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