Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone R3] (IgG2a) to Human DEFA5 / Defensin 5
IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Rabbit Polyclonal (IgG) to Human DEFA5 / Defensin 5
Western blot, ELISA
Human DEFA5 / Defensin 5
Human (tested or 100% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
DEFA5 / Defensin 5 antibody was raised against a synthetic17-aa peptide sequence near the C-terminus of human mature alpha defensin-5 (KLH coupled).
Recognizes human alpha defensin-5. No significant homology exists with other alpha-defensins.
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml using ECL. ELISA: 0.5-1 ug/ml. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.2. No preservative, no stabilizing protein added.
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8.