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DEFA1 / Defensin Alpha 1

defensin, alpha 1

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Gene Name: defensin, alpha 1
Synonyms: DEFA1, DEFA2, Defensin, alpha 2, HP-1, HP1, Myeloid-related sequence, MRS, DEF1, Defensin, alpha 1, HNP-1, Neutrophil defensin 1
Target Sequences: NM_004084 NP_004075.1 P59665

☰ Filters
Antibodies (40)
ELISA Kits (17)
Proteins (12)
Development Kit (1)
Over-Expression Lysate (2)
Primary (40)
Recombinant (10)
Sandwich (14)
Sandwich CLIA (2)
DEFA1 / Defensin Alpha 1 (69)
Human (49)
Mouse (2)
Rat (2)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Sheep (1)
IHC (9)
IHC-Fr (1)
IHC-P (6)
WB (36)
Flo (1)
ELISA (16)
IF (1)
Neut (6)
Peptide-ELISA (2)
rabbit (30)
mouse (1)
goat (9)
Product Group
DevKit DuoPlus (1)
IHCPlus (5)
Ig (1)
IgG (15)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (39)
DEF-3 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (12)
Antibody Pair and Standard (1)
APC (2)
APC Conjugated (3)
Biotin Conjugated (4)
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FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (20)
aa18-94 (8)
aa20-94 (8)
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Ser52 (1)
aa1-94 (1)
aa3-52 (1)
aa50-63 (1)
No (69)
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GST-6His, N-terminus (1)
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Human (8)
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293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
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Low endotoxin level (1)
Biologically active (2)
DEFA1 / Defensin Alpha 1 Antibody - Anti-DEFA1 / NP-1 antibody IHC of human thymus, myeloid cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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DEFA1 / Defensin Alpha 1 Goat anti-Human Polyclonal (aa50-63) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
DEFA1 / Defensin Alpha 1 Antibody - Anti-DEFA1 / NP-1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DEFA1 / Defensin Alpha 1 Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
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DEFA1 / Defensin Alpha 1 Goat anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
DEFA1 / Defensin Alpha 1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
DEFA1 / Defensin Alpha 1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:200.
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DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
DEFA1 / Defensin Alpha 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
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DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
DEFA1 / Defensin Alpha 1 Antibody - Immunohistochemistry analysis of Defensin α1 antibody in paraffin-embedded human breast carcinoma tissue.
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DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal (aa3-52) Antibody
Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
DEFA1 / Defensin Alpha 1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
DEFA1 / Defensin Alpha 1 Protein - Recombinant Defensin Alpha 1, Neutrophil By SDS-PAGE
Select
E. coli
His
9.8 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
DEFA1 / Defensin Alpha 1 Protein - Recombinant Defensin Alpha 1, Neutrophil By SDS-PAGE
Select
E. coli
His-GST
38.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
DEFA1 / Defensin Alpha 1 Protein - Recombinant  Defensin Alpha 2 By SDS-PAGE
Select
E. coli
His-GST
38.4 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
DEFA1 / Defensin Alpha 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Select
DEFA1 / Defensin Alpha 1 Mouse anti-Human Monoclonal (DEF-3) Antibody
Human
Flo, IHC-Fr, IHC-P, WB
Unconjugated
25 µg/$395
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DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
DEFA1 / Defensin Alpha 1 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using DEFA1 Polyclonal Antibody at dilution of 1:15.
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DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DEFA1 / Defensin Alpha 1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 µg/ml
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DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal (aa1-94) Antibody
Human
ELISA, IHC-P
Unconjugated
50 µl/$460
Select
DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DEFA1 / Defensin Alpha 1 Antibody - To detect hNP-1 by Western Blot analysis this antibody can be used at a concentration of 0.1- 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hNP-1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Select
DEFA1 / Defensin Alpha 1 Goat anti-Human Polyclonal Antibody
Human
ELISA, Neut, WB
Unconjugated
50 µg/$494
Select
DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
Select
DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
DEFA1 / Defensin Alpha 1 Antibody - All lanes: Anti-DEFA1 Antibody (Center) at 1:1000 dilution Lane 1: Human spleen lysate Lane 2: Human liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 10 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
DEFA1 / Defensin Alpha 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
Select
DEFA1 / Defensin Alpha 1 Goat anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, Neut, WB
Biotin Conjugated
100 µl/$860
Select
DEFA1 / Defensin Alpha 1 Goat anti-Human Polyclonal (APC) Antibody
Human
ELISA, Neut, WB
APC Conjugated
100 µl/$860
Select
DEFA1 / Defensin Alpha 1 Goat anti-Human Polyclonal (PE) Antibody
Human
ELISA, Neut, WB
PE Conjugated
100 µl/$860
Viewing 1-25 of 69 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).