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Anti-DEC-205 / CD205 / LY75 Antibody (clone NLDC-145, FITC) LS-C188787

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $520
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DEC-205 / CD205 / LY75 Antibodies

Anti-DEC-205 / CD205 / LY75 Antibody (C-Terminus) IHC-plus™ LS-B2669
Rabbit Polyclonal to Human DEC-205 / CD205 / LY75
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone NLDC-145] (IgG2a) to Mouse DEC-205 / CD205 / LY75
Mouse
IHC - Frozen, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated

Details

Mouse DEC-205 / CD205 / LY75
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [NLDC-145]
Fluorescein. Also available Unconjugated.
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Flow Cytometry (1:1 - 1:10)
  • (applications tested for the base form of this product only)

Specificity and Use

DEC-205 / CD205 / LY75 antibody was raised against mouse lymph node stroma.
Recognizes CD205, also known as DEC-205. CD205 is a 205kD integral membrane glycoprotein expressed by mouse dendritic cells and thymic epithelial cells. It is absent in bone marrow cells, all blood cells and freshly isolated macrophages from the peritoneal cavity. A subpopulation of the latter becomes positive in mice previously stimulated with thioglycollate. It is also absent on follicular dendritic cells of B cell follicles. DEC-205 is expressed at the cell surface of unfixed cells but can also be found in the cytoplasm of fixed cells.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About DEC-205 / CD205 / LY75

O60449 NM_002349 NP_002340.2

LY75 Antibody, CD205 Antibody, CLEC13B Antibody, CD205 antigen Antibody, LY-75 Antibody, Lymphocyte antigen 75 Antibody, DEC-205 Antibody, gp200-MR6 Antibody

LY75/CD205/DEC-205 is an integral membrane protein homologous to the macrophage mannose receptor and functions as an antigen-uptake receptor on dendritic cells. DEC-205 is rapidly taken up by means of coated pits and vesicles and is delivered to a multivesicular endosomal compartment that resembles the MHC class II-containing vesicles.

Immunohistochemistry

Immunohistochemistry
Immunoperoxidase staining of cryosectioned mouse lymph node with Rat anti-Mouse CD205. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry
Immunoperoxidase staining of mouse dendritic cells with Rat anti-Mouse CD205. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry
Immunofluorescent staining of Langerhans cells in mouse skin with Rat anti-Mouse CD205. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow Cytometry
Flow cytometry of mouse thymus cells with Rat anti-Mouse CD205:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/11/2016

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