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DDX5

DEAD (Asp-Glu-Ala-Asp) box helicase 5

Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR. Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specicic manner; the function probbaly involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.

Gene Name: DEAD (Asp-Glu-Ala-Asp) box helicase 5
Family/Subfamily: DEAD box protein
Synonyms: DDX5, DEAD box-5, HUMP68, HLR1, RNA helicase p68, RNA-dependent helicase p68, DEAD box protein 5, G17P1, HELR, p68
Target Sequences: NM_004396 NP_004387.1 P17844

☰ Filters
Antibodies (39)
Proteins (4)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (39)
Recombinant (2)
Sandwich (1)
DDX5 (44)
Human (40)
Mouse (25)
Rat (20)
Bat (8)
Bovine (8)
Chicken (3)
Chimpanzee (6)
Dog (7)
Gibbon (6)
Guinea pig (7)
Hamster (4)
Horse (8)
Monkey (7)
Orangutan (6)
Rabbit (8)
Sheep (1)
IHC (17)
IHC-P (9)
WB (32)
Flo (1)
DB (2)
ELISA (8)
ICC (6)
IF (17)
IP (6)
Peptide-ELISA (4)
rabbit (32)
mouse (6)
goat (1)
Product Group
IHCPlus (2)
IgG (25)
IgG1 (3)
IgG2a (2)
monoclonal mc (5)
polyclonal pc (34)
2257C3a (2)
4F1C12 (1)
96-Well Strip Plate (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Preservative Free (1)
Unconjugated (33)
N-Terminus (4)
aa544-593 (4)
540-620 aa (2)
C-Terminus (2)
aa575-C-term (2)
pTyr593 (2)
Asn589 (1)
aa1-290 (1)
aa306-334 (1)
aa448-614 (1)
aa491-518 (1)
aa550-600 (1)
aa565-614 (1)
aa566-580 (1)
aa602-614 (1)
No (44)
Tissue Homogenates (1)
10His, N-terminus + Myc, C-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Purified (1)
Select
DDX5 Rabbit anti-Human Polyclonal (540-620 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DDX5 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using DDX5/DEAD-box Protein 5 (Phospho-Tyr593) antibody.
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DDX5 Rabbit anti-Human Polyclonal (pTyr593) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
DDX5 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DDX5 Rabbit anti-Human Polyclonal (aa575-C-term) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
DDX5 Antibody - Immunohistochemical analysis of DDX5 (pY593) staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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DDX5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
DDX5 Antibody - Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-DDX5 mAb.
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DDX5 Mouse anti-Human Monoclonal (2257C3a) Antibody
Mouse, Rat, Human
DB, ICC, IF, IP, WB
Unconjugated
100 µg/$486
DDX5 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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DDX5 Rabbit anti-Human Polyclonal (aa1-290) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
DDX5 Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
DDX5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DDX5 Antibody - Immunohistochemistry of paraffin-embedded human thyroid cancer using DDX5 antibody at dilution of 1:200 (200x lens).
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DDX5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DDX5 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
DDX5 Rabbit anti-Human Polyclonal (aa575-C-term) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µl/$460
DDX5 Antibody - Immunohistochemistry of paraffin-embedded rat lung using DDX5 antibody at dilution of 1:100 (40x lens).
Select
DDX5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DDX5 Antibody - Anti-DDX5 rabbit polyclonal antibody at 1:500 dilution. Lane A: HeLa Whole Cell Lysate. Lane B: PC12 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 69 kDa. Observed band size: 70 kDa.
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DDX5 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IP, WB
Unconjugated, Preservative Free
100 µl/$412
DDX5 Antibody - Antibody staining (0.5 ug/ml) of A431 cell lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
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DDX5 Goat anti-Human Polyclonal (aa602-614) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$503
DDX5 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using DDX5/DEAD-box Protein 5 (Phospho-Tyr593) Antibody. The picture on the right is blocked with the phospho peptide.
Select
DDX5 Rabbit anti-Human Polyclonal (pTyr593) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Select
293T Cells
Myc-DDK (Flag)
69 kDa
20 µg/$150
DDX5 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His, N-terminus + Myc, C-terminus
74.1 kDa
1 mg/$1,486; 100 µg/$451; 20 µg/$339
DDX5 Antibody - DDX5 antibody. IHC(P): Rat Brain Tissue.
Select
DDX5 Rabbit anti-Human Polyclonal (aa566-580) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
DDX5 Antibody - Western blot of immunized recombinant protein using DDX5 antibody.
Select
DDX5 Mouse anti-Human Monoclonal (2257C3a) Antibody
Mouse, Rat, Human
DB, ICC, IP, WB
Unconjugated
100 µg/$965
Select
DDX5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
DDX5 Antibody - Western blot analysis of DDX5 expression in A431 (A); SHSY5Y (B) whole cell lysates.
Select
DDX5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, WB
Unconjugated
100 µl/$299
Select
DDX5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
DDX5 Antibody - Western blot of p68 RNA Helicase antibody
Select
DDX5 Rabbit anti-Human Polyclonal (540-620 aa) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
DDX5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Select
DDX5 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
50 µg/$558
Select
DDX5 Mouse anti-Human Monoclonal (4F1C12) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
DDX5 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with DDX5 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
DDX5 Rabbit anti-Human Polyclonal (aa491-518) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Viewing 1-25 of 44 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).