Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse (tested or 100% immunogen sequence identity)
Specificity and Use
DDX23 / PRP28 antibody was raised against the epitope recognized maps to a region between residue 775 and the C-terminus (residue 820) of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 using the numbering given in entry NP_004809.2 (GeneID 9416).
Species cross-reactivity: Human and mouse. Other species have not been tested.
Suitable for use in Western Blot and Immunoprecipitation.
DDX23 / PRP28 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.