Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse (tested or 100% immunogen sequence identity)
Specificity and Use
DDX19B antibody was raised against a synthetic peptide mapping to a region between residue 450 and the C-terminus (residue 479) of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B using the numbering given in entry NP_009173.1 (GeneID 11269). The epitope is highly conserved with DDX19A (GeneID 55308), but cross-reactivity of the antibody with this homolog has not been assessed.
Species cross-reactivity: Human and mouse. Other species have not been tested.
Suitable for use in Western Blot and Immunoprecipitation.
DDX19B Antibody, DBP5 Antibody, DDX19 Antibody, DEAD box RNA helicase DEAD5 Antibody, DEAD-box protein 5 Antibody, DEAD box protein 19B Antibody, DEAD-box RNA helicase DEAD5 Antibody, Yeast Dbp5 homolog Antibody, RNAH Antibody, TDBP Antibody
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.