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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DDC / DOPA Decarboxylase Antibody LS‑C22909
Antibody
DOPA Decarboxylase antibody LS-C22909 is an unconjugated rabbit polyclonal antibody to DOPA Decarboxylase (DDC) from human, rat, bovine and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C22909-100
100 µl
Unavailable

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Product Description

DOPA Decarboxylase antibody LS-C22909 is an unconjugated rabbit polyclonal antibody to DOPA Decarboxylase (DDC) from human, rat, bovine and other species. Validated for IHC and WB.
About DDC / DOPA Decarboxylase
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. P20711 NM_000790 NP_000781.1

DDC Antibody, AADC Antibody, DOPA decarboxylase Antibody


Specifications

Target
Human DDC / DOPA Decarboxylase
Host
Rabbit
Reactivity
Human, Rat, Bovine, Dog, Guinea pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, AP, APC, Biotin, FITC, HRP, PE.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1:500 - 1:1000)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant bovine DDC expressed in E. coli and purified from inclusion bodies.
Specificity
Recognizes DOPA Decarboxylase (DDC) at ~55kD by Western Blot on rat adrenal medulla. Species cross-reactivity: Human, sheep, canine, bovine, rabbit (low), rat and guinea pig adrenal samples.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:500-1:1000. Immunohistochemistry: Formaldehyde-fixed brain sections.
Presentation
10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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