DCPS

decapping enzyme, scavenger

Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP (PubMed:22985415). May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP (PubMed:14523240). Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death.

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Products

Antibodies (25)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (25)

Recombinant (3)

Target

DCPS (30)

Reactivity

Human (25)

Mouse (6)

Rat (2)

Application

IHC (6)

IHC-P (5)

WB (23)

ELISA (8)

ICC (1)

IF (2)

IP (2)

Host

rabbit (19)

mouse (6)

Isotype

IgG (18)

IgG1 (4)

IgG2a,k (1)

IgG2b,k (1)

Clonality

monoclonal mc (6)

polyclonal pc (19)

Clone

1G4 (1)

3E5 (1)

OTI1E6 (2)

OTI4H8 (2)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (2)

Carrier-free (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (15)

Epitope

aa165-193 (7)

aa1-50 (1)

aa287-337 (1)

Publications

No (30)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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DCPS Antibody (clone 1G4) LS-C133735

Antibody:

DCPS Mouse anti-Human Monoclonal (1G4) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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DCPS Antibody (clone OTI1E6) LS-C174320

Antibody:

DCPS Mouse anti-Human Monoclonal (OTI1E6) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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DCPS Antibody (clone OTI1E6, Carrier-free) LS-C787599

Antibody:

DCPS Mouse anti-Human Monoclonal (Carrier-free) (OTI1E6) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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DCPS Antibody (clone OTI4H8) LS-C174441

Antibody:

DCPS Mouse anti-Human Monoclonal (OTI4H8) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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DCPS Antibody (clone OTI4H8, Carrier-free) LS-C787761

Antibody:

DCPS Mouse anti-Human Monoclonal (Carrier-free) (OTI4H8) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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Human DCPS Protein (Recombinant His) - LS-G1383

Source:

E. coli

Tag:

His

Price:

50 µg/$392; 250 µg/$872; 10 µg/$286; 20 µg/$348; 100 µg/$511; 500 µg/$1,355

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DCPS Antibody LS-C816218

Antibody:

DCPS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

50 µl/$317; 100 µl/$375; 200 µl/$473

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DCPS Antibody (clone 3E5) LS-C105135

Antibody:

DCPS Mouse anti-Human Monoclonal (3E5) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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DCPS Antibody LS-C155445

Antibody:

DCPS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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DCPS Antibody (aa165-193) LS-C320762

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa165-193) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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DCPS Antibody (aa165-193, Biotin) LS-C255941

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa165-193) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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DCPS Antibody (aa165-193, FITC) LS-C255942

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa165-193) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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DCPS Antibody (aa165-193, PE) LS-C255944

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa165-193) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

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DCPS Antibody (aa165-193, APC) LS-C255940

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa165-193) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DCPS Antibody (aa165-193, Azide-free, HRP) LS-C255945

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa165-193) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

Select

DCPS Antibody (aa287-337) LS-C762959

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa287-337) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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DCPS Antibody LS-C310092

Antibody:

DCPS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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DCPS Antibody (HRP) LS-C541734

Antibody:

DCPS Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

DCPS Antibody (Biotin) LS-C521603

Antibody:

DCPS Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

DCPS Antibody (PE) LS-C649846

Antibody:

DCPS Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

Select

DCPS Antibody (APC) LS-C513387

Antibody:

DCPS Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • PE
  • APC

Select

DCPS Antibody (aa165-193) LS-C167300

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa165-193) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

DCPS Antibody LS-C497006

Antibody:

DCPS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

DCPS Antibody LS-C832823

Antibody:

DCPS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

DCPS Antibody (aa1-50) LS-C762941

Antibody:

DCPS Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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