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Anti-DCLRE1C / Artemis Antibody (aa677-692) IHC-plus™ LS-B665

Note: This antibody replaces LS-C2607

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml Unavailable

Most Popular DCLRE1C / Artemis Antibodies

Anti-DCLRE1C / Artemis Antibody (aa482-495) IHC-plus™ LS-B66
Goat Polyclonal to Human DCLRE1C / Artemis
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-DCLRE1C / Artemis Antibody (aa677-692) IHC-plus™ LS-B665
Rabbit Polyclonal to Human DCLRE1C / Artemis
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-DCLRE1C / Artemis Antibody (aa482-531) LS-C117627
Rabbit Polyclonal (IgG) to Human DCLRE1C / Artemis
Human
IHC - Paraffin, Immunofluorescence, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human DCLRE1C / Artemis
Human
IHC - Paraffin
Unconjugated

Details

Human DCLRE1C / Artemis
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

IHC - Paraffin (5 µg/ml)

Specificity and Use

DCLRE1C / Artemis antibody was raised against a synthetic peptide made to residues 677-692 [GESIAVKKRKCSLLDT] of the human Artemis protein Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Baboon (94%); Marmoset (88%); Orangutan, Bat, Rabbit, Horse (81%).
aa677-692
Artemis.
Immunohistochemistry: LS-B665 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B665 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About DCLRE1C / Artemis

Q96SD1 NM_022487 NP_071932.2

DCLRE1C Antibody, A-SCID Antibody, ARTEMIS Antibody, DCLREC1C Antibody, HSNM1C Antibody, SCIDA Antibody, RS-SCID Antibody, SNM1C Antibody, SNM1-like protein Antibody, Protein A-SCID Antibody, Protein artemis Antibody, PSO2 homolog Antibody, ASCID Antibody, DNA cross-link repair 1C Antibody, SNM1 homolog C Antibody

Required for V(D)J recombination, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, (D), and J gene segments. V(D)J recombination is initiated by the lymphoid specific RAG endonuclease complex, which generates site specific DNA double strand breaks (DSBs). These DSBs present two types of DNA end structures: hairpin sealed coding ends and phosphorylated blunt signal ends.

Immunohistochemistry

Immunohistochemistry
Anti-DCLRE1C / ARTEMIS antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B665 concentration 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-DCLRE1C / ARTEMIS antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B665 concentration 5 ug/ml.

Requested From: 
Date Requested: 3/24/2017

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