DCLRE1B

DNA cross-link repair 1B

5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint.

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Products

Antibodies (19)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (19)

Recombinant (1)

Target

DCLRE1B (22)

Reactivity

Human (19)

Mouse (9)

Application

IHC (9)

IHC-P (2)

WB (15)

Flo (2)

ELISA (12)

IF (2)

Peptide-ELISA (1)

Host

rabbit (17)

mouse (2)

Isotype

IgG (15)

IgG1 (2)

Clonality

monoclonal mc (2)

polyclonal pc (17)

Clone

OTI2B7 (2)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

Carrier-free (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (11)

Epitope

aa208-236 (7)

aa1-280 (2)

C-Terminus (1)

C-terminal (1)

Publications

No (21)

Yes (1)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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DCLRE1B Antibody (aa208-236) LS-C167295

(4.0) Rating

(1) Publication(s)

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (aa208-236) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Human DCLRE1B Protein (Recombinant GST) (Full Length) - LS-G35052

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

86.4 kDa

Price:

2 µg/$439

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DCLRE1B Antibody (aa1-280, clone OTI2B7) LS-C337240

Antibody:

DCLRE1B Mouse anti-Human Monoclonal (aa1-280) (OTI2B7) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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DCLRE1B Antibody (aa1-280, clone OTI2B7, Carrier-free) LS-C785575

Antibody:

DCLRE1B Mouse anti-Human Monoclonal (aa1-280) (Carrier-free) (OTI2B7) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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DCLRE1B Antibody (C-Terminus) LS-C353534

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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DCLRE1B Antibody (aa208-236) LS-C320763

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (aa208-236) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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DCLRE1B Antibody (aa208-236, Biotin) LS-C234457

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (aa208-236) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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DCLRE1B Antibody (aa208-236, FITC) LS-C234458

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (aa208-236) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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DCLRE1B Antibody (aa208-236, APC) LS-C234455

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (aa208-236) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DCLRE1B Antibody (aa208-236, PE) LS-C234462

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (aa208-236) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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DCLRE1B Antibody (aa208-236, Azide-free, HRP) LS-C249803

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (aa208-236) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

DCLRE1B Antibody LS-C680365

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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DCLRE1B Antibody (HRP) LS-C680369

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

DCLRE1B Antibody (Biotin) LS-C680368

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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DCLRE1B Antibody (FITC) LS-C680367

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DCLRE1B Antibody LS-C665006

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

DCLRE1B Antibody (C-terminal) LS-C386824

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal (C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

DCLRE1B Antibody LS-C807930

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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DCLRE1B Antibody LS-C409042

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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DCLRE1B Antibody LS-C834378

Antibody:

DCLRE1B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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DCLRE1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110219

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.8 kDa

Price:

100 µg/$494

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Human DCLRE1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91696

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.8 kDa

Price:

20 µg/$150

Viewing 1-22 of 22 product results

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