Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
DAND5 antibody was raised against synthetic peptide from N-Terminus of human DAND5 (Q8N907, NP_689867). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%); Orangutan (91%); Monkey (85%).
DAND5 Antibody, CERL2 Antibody, Cerberus-like protein 2 Antibody, DAN domain family, member 5 Antibody, DANTE Antibody, CER2 Antibody, Cerberus-like 2 Antibody, DAN domain family member 5 Antibody, CKTSF1B3 Antibody, COCO Antibody, DTE Antibody, GREM3 Antibody, Gremlin-3 Antibody, Cerberus 2 Antibody, Cerl-2 Antibody, CRL2 Antibody
DAND5 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins.