Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Western blot
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen (1:50 - 1:100)
Specificity and Use
Cytokeratin 5+6 antibody was raised against purified cytokeratin 5.
Recognizes human cytokeratin 5. Demonstrates cross-reactivity with cytokeratin 6. Demonstrates weak cross-reactivity with cytokeratin 4 on immunoblots. Does not cross-react with cytokeratins 1, 7, 8, 10, 13, 14, 18 or 19. Recognizes basal cells and a part of stratum spinosum in the normal pavement epithelium.
Suitable for use in Immunohistochemistry, Western Blot, Immunofluorescence. Immunohistochemistry (frozen or paraffin sections): 1:50-1:100. Western Blot: Recognizes a 58kD and 56kD band corresponding to cytokeratin 5 and 6. Cytoskeletal preparations of epidermis.