Human Cytokeratin 5+14

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 + IgG3 Monoclonal

Unconjugated

Purified

Ready-to-Use

Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-Terminus of the human cytokeratin 5 molecule. LLLLL: Synthetic peptide of the extreme C-Terminus of human keratin-14.

C-Terminus

This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58kD protein, which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15. This antibody can be useful to distinguish stratified epithelial cells from simple epithelial cells. Species cross-reactivity: This antibody is reactive against human.

• IHC
• IHC - Frozen
• ICC
• Immunofluorescence

Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (Fr) and Immunocytochemistry. Positive control: Skin.

PBS, pH 7.2, 0.08% sodium azide.

Do not freeze. Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Freezing will result in a substantial loss of activity.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.