CYR61

cysteine-rich, angiogenic inducer, 61

Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

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Products

Antibodies (40)

ELISA Kits (18)

Proteins (14)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (40)

Recombinant (12)

Sandwich (16)

Sandwich CLIA (1)

Target

CYR61 (72)

Reactivity

Human (38)

Mouse (22)

Rat (10)

Bat (3)

Chicken (2)

Chimpanzee (3)

Gibbon (3)

Horse (3)

Monkey (4)

Porcine (1)

Rabbit (4)

Sheep (1)

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Application

IHC (10)

IHC-Fr (1)

IHC-P (4)

WB (33)

ELISA (11)

ICC (1)

IF (1)

Peptide-ELISA (1)

Host

rabbit (35)

mouse (2)

rat (1)

sheep (2)

Product Group

IHCPlus (2)

Isotype

IgG (12)

IgG1,k (1)

IgG2a,k (1)

IgG2b (1)

Clonality

monoclonal mc (3)

polyclonal pc (37)

Clone

3C11 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (3)

96-Well Strip Plate (14)

APC (2)

APC Conjugated (2)

Biotin Conjugated (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (20)

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Epitope

aa176-379 (8)

aa178-381 (8)

aa100-149 (4)

aa120-220 (1)

aa143-174 (1)

aa150-250 (1)

aa168-242 (1)

aa176-281 (1)

aa22-381 (1)

aa47-332 (1)

aa54-381 (1)

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Publications

No (72)

Sample Type

Breast Milk (1)

Cell Culture Supernatants (3)

Cell Lysates (1)

Plasma (13)

Saliva (2)

Serum (13)

Tissue Homogenates (5)

Urine (2)

Tag

10His, N-terminus (1)

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

Fc, C-terminus (2)

GST (2)

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (2)

Species

Human (10)

Mouse (3)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (3)

Yeast (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (3)

Biologically Active

Biologically active (2)

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CYR61 Antibody (aa176-281) LS-C64183

Antibody:

CYR61 Rat anti-Mouse Monoclonal (aa176-281) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$884

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Mouse CYR61 (Sandwich ELISA) ELISA Kit - LS-F8609

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

6.25 - 400 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

Select

Human CYR61 Protein (Recombinant) - LS-G93

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

39.5 kDa

Price:

5 µg/$268; 20 µg/$349

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Mouse CYR61 (Sandwich ELISA) ELISA Kit - LS-F14642

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human CYR61 (Sandwich ELISA) ELISA Kit - LS-F2883

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Breast Milk, Cell Culture Supernatants, Plasma, Saliva, Serum, Urine

Price:

1 Plate/$1,150

Select

CYR61 Antibody LS-C401576

Antibody:

CYR61 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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CYR61 Antibody (aa178-381, PE) LS-C727645

Antibody:

CYR61 Rabbit anti-Human Polyclonal (aa178-381) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

IHC-plus™ CYR61 Antibody (aa150-250) LS-B13180

(4.0) Rating

Antibody:

CYR61 Rabbit anti-Human Polyclonal (aa150-250) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$485

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Rat CYR61 (Sandwich ELISA) ELISA Kit - LS-F14640

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Mouse CYR61 Protein (Recombinant 6His, N-terminus) (aa25-379) - LS-G22885

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

41.14 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human CYR61 Protein (Recombinant) (aa25-381) - LS-G5810

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

39.4 kDa

Price:

5 µg/$282; 100 µg/$1,186; 500 µg/$2,269

Select

IHC-plus™ CYR61 Antibody (aa47-332) LS-B11602

(4.0) Rating

Antibody:

CYR61 Rabbit anti-Human Polyclonal (aa47-332) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$575

Select

Mouse CYR61 (Sandwich ELISA) ELISA Kit - LS-F53030

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$870

Select

Human CYR61 Protein (Recombinant Fc, C-terminus) (Thr25-Asp381) - LS-G39376

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

66.5kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human CYR61 Protein (Recombinant 6His-SUMO, N-terminus) (aa25-381) - LS-G56201

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human CYR61 (Sandwich ELISA) ELISA Kit - LS-F23438

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse CYR61 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G136992

Source:

E. coli

Tag:

10His, N-terminus

Molecular Weight:

42.6 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

Select

CYR61 Antibody LS-C121688

Antibody:

CYR61 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Sheep, Rat, Human

Applications:

IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

20 µl/$508; 100 µl/$996

Select

CYR61 Antibody (aa168-242) LS-C123359

Antibody:

CYR61 Mouse anti-Human Monoclonal (aa168-242) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$586

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CYR61 Antibody LS-C64184

Antibody:

CYR61 Sheep anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$930

Select

CYR61 Antibody LS-C404865

Antibody:

CYR61 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CYR61 Antibody LS-C500205

Antibody:

CYR61 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CYR61 Antibody (aa120-220) LS-C335126

Antibody:

CYR61 Rabbit anti-Human Polyclonal (aa120-220) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

CYR61 Antibody LS-C746307

Antibody:

CYR61 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$448

Select

CYR61 Antibody LS-C780778

Antibody:

CYR61 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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