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Anti-CYR61 Antibody (aa250-350, Biotin) LS-C142796

Catalog Size Price
LS-C142796-100 100 µl Unavailable

Related Products

46 CYR61 Antibodies

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Anti-CYR61 Antibody (aa250-350) LS-C49074
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Western blot Image
Anti-CYR61 Antibody (aa176-281) LS-C64183
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Anti-CYR61 Antibody (aa168-242, clone 3H3) IHC-plus™ LS-B2959
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Anti-CYR61 Antibody IHC-plus™ LS-B8746
Rabbit Polyclonal (IgG) to Mouse CYR61
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Anti-CYR61 Antibody (aa150-250) IHC-plus™ LS-B13180
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100% Guaranteed
Rabbit Polyclonal to Human CYR61
Human, Rat
ICC, Immunofluorescence, Western blot (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human CYR61
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Mouse, Rat
Polyclonal
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Immunoaffinity purified
Unmodified

Applications

  • ICC
  • Immunofluorescence
  • Western blot (1:200)
  • (applications tested for the base form of this product only)

Specificity and Use

CYR61 antibody was raised against a synthetic peptide made to the human CYR61 protein sequence (between residues 250-350) Percent identity by BLAST analysis: Rat (100%); Mouse (96%).
aa250-350
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS
Store at 4°C. Do not freeze.
For research use only.

About CYR61

O00622 NM_001554 NP_001545.2

CYR61 Antibody, GIG1 Antibody, IGFBP10 Antibody, Protein CYR61 Antibody, CCN family member 1 Antibody, CCN1 Antibody, IBP-10 Antibody, IGF-binding protein 10 Antibody, IGFBP-10 Antibody, Protein GIG1 Antibody

Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1.

Western blot

Western blot
Detection of cleaved CYR61 in MDA-MB-231 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 6/26/2017

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