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Anti-CYR61 Antibody (aa176-281) LS-C64183

Catalog Size Price
LS-C64183-100 100 µg (0.5 mg/ml) Unavailable

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46 CYR61 Antibodies

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100% Guaranteed
Rat Monoclonal (IgG2b) to Mouse CYR61
Mouse
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Unconjugated

Details

Mouse CYR61
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC (25 µg/ml)
  • Western blot (2 µg/ml)
  • ELISA (0.5 - 1 µg/ml)

Specificity and Use

CYR61 antibody was raised against e. coli-derived rmCyr61. (aa 176 - 281).
aa176-281
Recognizes mouse Cyr61.
Suitable for use in Direct ELISA, Immunohistochemistry and Western Blot. Direct ELISA: 0.5-1.0 ug/ml. Detection limit is ~5 ng/well. Western Blot: 2 ug/ml. Immunohistochemistry: 25 ug/ml.

Packaging

Lyophilized from PBS, 5% trehalose.
200 µl Sterile PBS
Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid frequent freeze thaws.
For research use only.

About CYR61

O00622 NM_001554 NP_001545.2

CYR61 Antibody, GIG1 Antibody, IGFBP10 Antibody, Protein CYR61 Antibody, CCN family member 1 Antibody, CCN1 Antibody, IBP-10 Antibody, IGF-binding protein 10 Antibody, IGFBP-10 Antibody, Protein GIG1 Antibody

Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1.

Requested From: 
Date Requested: 11/23/2017

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