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CYP3A43 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | cytochrome P450, family 3, subfamily A, polypeptide 43 |
Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
Synonyms: | CYP3A43, Cytochrome P450 3A43, Cytochrome P450 polypeptide 43 |
Target Sequences: | NM_022820 NP_073731.1 Q9HB55 |
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