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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CYP2C9 / Cytochrome P450 2C9 Antibody LS‑C42882
Cytochrome P450 2C9 antibody LS-C42882 is an unconjugated rabbit polyclonal antibody to human Cytochrome P450 2C9 (CYP2C9). Validated for Func and WB.
Antibody
Catalog
Size
Price
LS-C42882-50
50 µl
Unavailable

Popular CYP2C9 / Cytochrome P450 2C9 Products

Antibody
Species: Human
Applications: Western blot, Functional Assay
CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CYP2C9 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Western blot analysis of Cytochrome P450 2C9 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Species: Human, Mouse, Rat
Applications: Western blot

Product Description

Cytochrome P450 2C9 antibody LS-C42882 is an unconjugated rabbit polyclonal antibody to human Cytochrome P450 2C9 (CYP2C9). Validated for Func and WB.
About CYP2C9 / Cytochrome P450 2C9
CYP2C9 / Cytochrome P450 2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. P11712 NM_000771 NP_000762.2

CYP2C9 Antibody, Cytochrome P450 PB-1 Antibody, Cytochrome P-450MP Antibody, CYP2C10 Antibody, CYPIIC9 Antibody, Cytochrome P450 2C9 Antibody, Cytochrome P450 MP-4 Antibody, Cytochrome P450 MP-8 Antibody, p450IIC9 Antibody, S-mephenytoin 4-hydroxylase Antibody, CPC9 Antibody, CYP2C Antibody


Specifications

Target
Human CYP2C9 / Cytochrome P450 2C9
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:5000 - 1:10000)
  • Functional Assay
Immunogen
Recombinant human CYP2C9.
Specificity
Recognizes human cytochrome p450 2C9 (CYP2C9). P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members: CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. Which is a potent inhibitor of CYP2C9 activity. Inhibition of CYP2C19 activity has also been observed.
Presentation
Serum.
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/17/2018

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