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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CYP2C9 / Cytochrome P450 2C9 Antibody (aa82‑110) LS‑C97486
Cytochrome P450 2C9 antibody LS-C97486 is an unconjugated rabbit polyclonal antibody to human Cytochrome P450 2C9 (CYP2C9). Validated for IHC and WB.
Catalog
Size
Price
LS-C97486-400
400 µl
Unavailable

Popular CYP2C9 / Cytochrome P450 2C9 Products

Antibody
Species: Human
Applications: Western blot, Functional Assay
Antibody
Species: Human
Applications: Western blot, Functional Assay
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CYP2C9 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Western blot analysis of Cytochrome P450 2C9 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Species: Human, Mouse, Rat
Applications: Western blot

Product Description

Cytochrome P450 2C9 antibody LS-C97486 is an unconjugated rabbit polyclonal antibody to human Cytochrome P450 2C9 (CYP2C9). Validated for IHC and WB.
About CYP2C9 / Cytochrome P450 2C9
CYP2C9 / Cytochrome P450 2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. P11712 NM_000771 NP_000762.2

CYP2C9 Antibody, Cytochrome P450 PB-1 Antibody, Cytochrome P-450MP Antibody, CYP2C10 Antibody, CYPIIC9 Antibody, Cytochrome P450 2C9 Antibody, Cytochrome P450 MP-4 Antibody, Cytochrome P450 MP-8 Antibody, p450IIC9 Antibody, S-mephenytoin 4-hydroxylase Antibody, CPC9 Antibody, CYP2C Antibody


Specifications

Target
Human CYP2C9 / Cytochrome P450 2C9
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E9335 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C97486. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa82-110
Specificity
This CYP2C9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of human CYP2C9.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.
Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.

Immunohistochemistry

CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.
Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.

Immunohistochemistry

CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.
Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.

Immunohistochemistry

CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CYP2C9 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.
Western blot of anti-CYP2C9 Antibody in Jurkat cell line lysates (35 ug/lane). CYP2C9(arrow) was detected using the purified antibody.


Requested From: 
Date Requested: 6/23/2018

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