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CYP2A6

cytochrome P450, family 2, subfamily A, polypeptide 6

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.

Gene Name: cytochrome P450, family 2, subfamily A, polypeptide 6
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP2A6, CYP2A, Cytochrome P450(I), CYPIIA6, p450PB, p450C2A, Coumarin 7-hydroxylase, CYP2A3, Cytochrome P450 2A6, Cytochrome P450 IIA3
Target Sequences: NM_000762 AAB40518.1 P11509

☰ Filters
Antibodies (48)
Proteins (4)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (48)
Recombinant (2)
Sandwich (2)
CYP2A6 (54)
Human (50)
Mouse (4)
Rat (3)
Chimpanzee (3)
Gibbon (3)
Monkey (3)
IHC (14)
IHC-P (5)
WB (43)
Flo (8)
ELISA (7)
ICC (1)
IF (13)
Peptide-ELISA (4)
rabbit (35)
mouse (13)
IgG (21)
IgG1 (1)
IgG2a (2)
IgG2a,k (1)
IgG2b (8)
monoclonal mc (12)
polyclonal pc (36)
3B11 (1)
OTI1D2 (2)
OTI2A8 (2)
OTI3C1 (2)
OTI5F8 (2)
OTI9G3 (2)
96-Well Strip Plate (2)
APC Conjugated (1)
Biotin Conjugated (4)
Carrier-free (5)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (34)
C-Terminus (4)
aa352-401 (4)
10-90 aa, N-terminal (1)
Glu131 (1)
Internal (1)
N-Terminus (1)
aa1-494 (1)
aa1-50 (1)
No (54)
Plasma (2)
Serum (2)
Tissue Homogenates (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
CYP2A6 Antibody - Immunofluorescent analysis of Cytochrome P450 2A6 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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CYP2A6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$299
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.
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CYP2A6 Mouse anti-Human Monoclonal (OTI3C1) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.
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CYP2A6 Mouse anti-Human Monoclonal (Carrier-free) (OTI3C1) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CYP2A6 Mouse anti-Human Monoclonal (OTI9G3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CYP2A6 Mouse anti-Human Monoclonal (Carrier-free) (OTI9G3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.
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CYP2A6 Mouse anti-Human Monoclonal (OTI2A8) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.
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CYP2A6 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CYP2A6 Mouse anti-Human Monoclonal (OTI5F8) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CYP2A6 Mouse anti-Human Monoclonal (Carrier-free) (OTI5F8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.
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CYP2A6 Mouse anti-Human Monoclonal (OTI1D2) Antibody
Mouse, Rat, Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP2A6 Antibody - IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.
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CYP2A6 Mouse anti-Human Monoclonal (Carrier-free) (OTI1D2) Antibody
Mouse, Rat, Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP2A6 Antibody - CYP2A6 antibody Western Blot of Fetal Small Intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP2A6 Rabbit anti-Human Polyclonal (aa352-401) (HRP) Antibody
Human, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
CYP2A6 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CYP2A6 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYP2A6 Antibody - Left: Western blot of CYP2A6 antibody (Cytochrome P450 2A6) on recombinant cytochrome p450 at 1 ug/ml. Right: Staining using CYP2A6 antibody on normal human liver tissue at 1 ug/ml.
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CYP2A6 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µg/$466
CYP2A6 Antibody - Western blot of CYP2A6 antibody
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CYP2A6 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP2A6 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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CYP2A6 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CYP2A6 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$649
CYP2A6 Antibody - Western blot of CYP2A6 (E131) pAb in extracts from Jurkat cells.
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CYP2A6 Rabbit anti-Human Polyclonal (Glu131) Antibody
Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
CYP2A6 Antibody - Western blot analysis of extracts of various cell lines.
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CYP2A6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CYP2A6 Antibody - Detection limit for recombinant GST tagged CYP2A6 is 3 ng/ml as a capture antibody.
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CYP2A6 Mouse anti-Human Monoclonal (3B11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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CYP2A6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
CYP2A6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CYP2A6 Antibody - Positive Western Blot detected in Rat heart tissue. All lanes: CYP2A6 antibody at 3 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 57 KDa. Observed band size: 57 KDa
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CYP2A6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CYP2A6 Antibody - Western blot analysis of extracts from Jurkat cells, using Cytochrome P450 2A6 antibody.
Select
CYP2A6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CYP2A6 Antibody - Western blot analysis of lysates from Jurkat cells, using Cytochrome P450 2A6 Antibody. The lane on the right is blocked with the synthesized peptide.
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CYP2A6 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 54 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).