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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CYP1A2 Antibody LS‑C22611
Antibody
CYP1A2 antibody LS-C22611 is an unconjugated goat polyclonal antibody to human CYP1A2. Validated for Func and WB.
Catalog
Size
Price
LS-C22611-500
500 µl
Unavailable

Popular CYP1A2 Products

Antibody
Species: Human, Rat
Applications: IHC, IHC - Frozen, Western blot
Immunohistochemical staining of paraffin-embedded liver tissue using anti-CYP1A2 mouse monoclonal antibody. (Dilution 1:50).
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
IHC of paraffin-embedded Human Kidney tissue using anti-CYP1A2 mouse monoclonal antibody. (Dilution 1:50).
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
IHC of paraffin-embedded Human pancreas tissue using anti-CYP1A2 mouse monoclonal antibody. (Dilution 1:50).
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
IHC of paraffin-embedded Human liver tissue using anti-CYP1A2 mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry

Product Description

CYP1A2 antibody LS-C22611 is an unconjugated goat polyclonal antibody to human CYP1A2. Validated for Func and WB.
About CYP1A2
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. P05177 NM_000761 NP_000752.2

CYP1A2 Antibody, Aryl hydrocarbon hydroxylase Antibody, Cytochrome P(3)450 Antibody, Cytochrome P450 1A2 Antibody, Cytochrome P450 4 Antibody, p450 form 4 Antibody, p3-450 Antibody, p450(PA) Antibody, CP12 Antibody, CYPIA2 Antibody, Cytochrome p450 ia2 Antibody, Cytochrome P450-P3 Antibody, Dioxin-inducible P3-450 Antibody


Specifications

Target
Human CYP1A2
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot
  • Functional Assay
Immunogen
CYP1A2 antibody was raised against recombinant human P450 1A2 expressed in E. coli.
Specificity
Reactive with 0.2 ug of recombinant human P450 1A2. Only slightly cross-reacts with recombinant human P450 1A1after prolonged incubation. Does not cross-react with recombinant human cytochromes P450 2E1, 3A4, or 2C10.
Usage
Suitable for use in inhibition assays and Western Blot. A dilution of 1:2000 for Western blots will yield a positive result with 0.2 ug of recombinant human cytochrome P450 IA2 using alkaline phosphatase-conjugated anti-goat IgG secondary antibody according to the manufacturer's instructions. Inhibits approximately 80% of the ethoxyresorufin O-deethylase activity of human liver microsomes at a concentration of 10 mg IgG/nmol P450. Western Blot: Recognizes a band (P450 1A2) in human liver microsomes.
Presentation
20 mM phosphate buffer, pH 8.0.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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