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Anti-CYP11B1 Antibody (aa202-251) LS-C135724

Catalog Size Price
LS-C135724-50 50 µg Unavailable

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25 CYP11B1 Antibodies

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Western blot Image

100% Guaranteed
Rabbit Polyclonal to Human CYP11B1
Human
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human CYP11B1
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

CYP11B1 antibody was raised against synthetic peptide located between aa202-251 of human CYP11B1 (P15538, NP_000488). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (92%).
LS-E22024 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C135724. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa202-251
Human CYP11B1
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CYP11B1

P15538 NM_000497 NP_000488.3

CYP11B1 Antibody, CYPXIB1 Antibody, Cytochrome P-450c11 Antibody, Cytochrome P450C11 Antibody, S11BH Antibody, Steroid 11-beta-hydroxylase Antibody, Steroid 11-beta-monooxygenase Antibody, CYP11B Antibody, Cytochrome p450 XIB1 Antibody, FHI Antibody, p450C11 Antibody

CYP11B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency.

Western blot

Western blot
CYP11B1 antibody LS-C135724 Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 12/18/2017

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