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| Catalog Number | Size | Price |
|---|---|---|
| LS-C179418-100 | 100 µg (1 mg/ml) | $430 |
Monoclonal Mouse anti‑Human CYBB / NOX2 / gp91phox Antibody (clone 7D5) LS‑C179418
Monoclonal Mouse anti‑Human CYBB / NOX2 / gp91phox Antibody (clone 7D5) LS‑C179418
Antibody:
CYBB / NOX2 / gp91phox Mouse anti-Human Monoclonal (7D5) Antibody
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CYBB / NOX2 / gp91phox Mouse anti-Human Monoclonal (7D5) Antibody
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Gp91phox antibody LS-C179418 is an unconjugated mouse monoclonal antibody to human gp91phox (CYBB / NOX2). Validated for Flow. Cited in 2 publications.
Target
Human CYBB / NOX2 / gp91phox
Synonyms
CYBB | Chronic granulomatous disease | CGD91-phox | Cytochrome b558 subunit beta | Cytochrome b(558) subunit beta | gp91-1 | gp91-PHOX | p22 phagocyte B-cytochrome | AMCBX2 | CGD | Cytochrome b-245 heavy chain | gp91PHOX | NADPH oxidase 2 | NOX2 | p91-PHOX
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
7D5
Conjugations
Unconjugated
Purification
Purified by Protein A agarose
Modifications
Unmodified
Immunogen
Rich fraction of human cytochrome b
Applications
- Flow Cytometry (5 µg/ml)
Usage
This antibody reacts with an extracellular epitope of CYBB / NOX2 / gp91phox. The antibody recognizes the epitope in the native conformation or after treatment with guanidine or urea, but SDS treatment will abolish antibody binding.
Presentation
PBS, pH 7.2, 50% Glycerol, No preservatives added
Storage
Store at -20°C for 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CYBB / NOX2 / gp91phox
LSBio Ratings
CYBB / NOX2 / gp91phox Antibody (clone 7D5) for Flow LS-C179418 has an LSBio Rating of
Publications (4.1)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive. Keszei M, Record J, Kritikou JS, Wurzer H, Geyer C, Thiemann M, Drescher P, Brauner H, Köcher L, James J, He M, Baptista MA, Dahlberg CI, Biswas A, Lain S, Lane DP, Song W, Pütsep K, Vandenberghe P, Snapper SB, Westerberg LS. The Journal of clinical investigation. 2018 August;128:4115-4131.
Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR. Becky A Diebold, S Garrett Wilder, Xavier De Deken, Jennifer L Meitzler, James H Doroshow, James W McCoy, Yerun Zhu, J David Lambeth. Methods in molecular biology (Clifton, N.J.). 2019 June;1982:191-229.
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Featured Products
Species:
Human
Applications:
Flow Cytometry
Species:
Human
Applications:
Flow Cytometry
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Bat
Applications:
Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Reactivity:
Human
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
