Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CXCR4 antibody was raised against cP-MAC infected Human Sup-T1 cells.
Recognizes human CXCR4 protein.
Suitable for use in Immunohistochemistry, Immunofluorescence and Flow Cytometry. Immunohistochemistry: 10 ug/ml. Immunofluorescence: 10 ug/ml. Do not use cells fixed in acetone or methanol. 3% paraformaldehyde has been shown to give optimal results. Flow Cytometry: 2-5 ug/ml. Positive control: Human lymphoid cell lines, human liver and brain tissues.
PBS, pH 7.4, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation.