Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 5E8-C7-F10] (IgG1,k) to Human CXCR2
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [5E8-C7-F10]
Specificity and Use
CXCR2 antibody was raised against human IL8RB
This 5E8-C7-F10 (5E8-C7-F10) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood. This can be used at 5 ul (0.25 ug)/per test. A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
CXCR2 Antibody, CDw128b Antibody, CD182 antigen Antibody, CMKAR2 Antibody, CXCR-2 Antibody, CD182 Antibody, CXC-R2 Antibody, IL-8R B Antibody, Il-8 receptor b Antibody, IL-8 receptor type 2 Antibody, Il-8rb Antibody, IL8R2 Antibody, IL8RB Antibody, Interleukin-8 receptor type B Antibody, GRO/MGSA receptor Antibody, Interleukin 8 receptor beta Antibody, Interleukin 8 receptor, beta Antibody, Chemokine (CXC) receptor 2 Antibody, IL8RA Antibody, Interleukin 8 receptor B Antibody, Interleukin 8 receptor type 2 Antibody
CXCR2 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth.
Staining of PE anti-human CD182 (5E8-C7-F10). Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of normal human peripheral blood cells with APC anti-human CD4 (OKT4) and PE anti-human CD182 (5E8-C7-F10). Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From: United States
Date Requested: 2/26/2017