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Anti-CXADR Antibody (Internal) IHC-plus™ LS-A8845

Catalog Size Price
LS-A8845-50 50 µg (1 mg/ml) Unavailable
Same day shipping In Stock - Same day shipping

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100% Guaranteed In Stock
Rabbit Polyclonal to Human CXADR
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Hamster, Horse, Pig, Rabbit
IHC - Paraffin
Unconjugated

Details

Human CXADR
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (10 µg/ml)

Specificity and Use

CXADR antibody was raised against synthetic 15 amino acid peptide from internal region of human CXADR. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine, Rabbit, Horse, Pig, Opossum, Guinea pig (100%); Zebra finch, Platypus, Lizard (93%); Xenopus, Stickleback, Pufferfish, Zebrafish (80%).
LS-E29500 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A8845. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Internal
Human CXADR. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Immunogenic peptide is present in isoforms 1 and 2 per Swiss-Prot P78310.
Immunohistochemistry: LS-A8845 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A8845 was determined to be 10 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About CXADR

P78310 NM_001338 NP_001329.1

CXADR Antibody, CAR4/6 Antibody, Coxsackie-adenovirus receptor Antibody, CVB3-binding protein Antibody, CAR Antibody, HCAR Antibody, HCVADR Antibody

Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes.

Immunohistochemistry

Immunohistochemistry
Anti-CXADR antibody LS-A8845 IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CXADR antibody LS-A8845 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 12/10/2017

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