Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
CUL5 / Cullin-5
cullin 5
Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
| Gene Name: | cullin 5 |
| Family/Subfamily: | Ion Channel |
| Synonyms: | CUL5, Cullin 5, CUL-5, VACM-1, VACM1, Cullin-5 |
| Target Sequences: | NM_003478 NP_003469.2 Q93034 |
Publications (2)
1
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM. Cell. 1996 85:829-39.
[PubMed:8681378]
Related Antibodies: LS-B361.
2
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Ohta T, Michel JJ, Schottelius AJ, Xiong Y. Molecular cell. 1999 3:535-41.
[PubMed:10230407]
Related Antibodies: LS-B361.
☰ Filters
Products
Antibodies
(18)
ELISA Kits
(4)
Proteins
(4)
Type
Custom
(2)
Over-Expression Lysate
(2)
Primary
(18)
Recombinant
(2)
Sandwich
(2)
Target
CUL5 / Cullin-5
(26)
Reactivity
Human
(20)
Mouse
(13)
Rat
(10)
Bat
(3)
Bovine
(4)
Chicken
(3)
Chimpanzee
(3)
Dog
(3)
Gibbon
(3)
Guinea pig
(3)
Hamster
(1)
Horse
(4)
Monkey
(4)
Orangutan
(3)
Pig
(3)
Rabbit
(4)
Xenopus
(4)
Zebrafish
(4)
Application
IHC
(8)
IHC-P
(6)
WB
(13)
Flo
(1)
ELISA
(8)
ICC
(1)
IF
(3)
IP
(2)
Peptide-ELISA
(1)
Host
rabbit
(18)
Product Group
IHCPlus
(2)
Isotype
IgG
(12)
Clonality
polyclonal pc
(18)
Format
96-Well Strip Plate
(4)
Biotin Conjugated
(1)
FITC Conjugated
(1)
HRP Conjugated
(1)
Unconjugated
(15)
Epitope
aa526-575
(4)
aa1-300
(2)
aa1-50
(2)
C-Terminus
(1)
aa1-25
(1)
aa4-19
(1)
aa747-774
(1)
Publications
No
(25)
Yes
(1)
Sample Type
Plasma
(2)
Serum
(2)
Tissue Homogenates
(1)
Tag
GST, N-terminus
(1)
Myc-DDK (Flag)
(3)
Species
Human
(3)
Source
293T Cells
(1)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa1-25) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$515
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa747-774) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IF, IHC, IHC-P
Unconjugated
100 µl/$470
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa4-19) Antibody
Xenopus, Zebrafish, Horse, Rat, Hamster, Rabbit, Mouse, Bovine, Human, Monkey
ELISA, ICC, WB
Unconjugated
1 mg/$901
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
100 µl/$332
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa526-575) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$397
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa526-575) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$442
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa526-575) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
Biotin Conjugated
100 µl/$442
CUL5 / Cullin-5 Rabbit anti-Human Polyclonal (aa526-575) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$442
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
293T Cells
Myc-DDK (Flag)
90.8 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
90.8 kDa
20 µg/$1,107
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Viewing 1-25
of 26
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
