CUL2 / Cullin 2

cullin 2

Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).

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Products

Antibodies (48)

Proteins (5)

ELISA Kits (1)

Type

Cell-Based (1)

Over-Expression Lysate (2)

Primary (48)

Recombinant (3)

Target

CUL2 / Cullin 2 (54)

Reactivity

Human (49)

Mouse (30)

Rat (11)

Bat (1)

Bovine (7)

Chicken (7)

Chimpanzee (3)

Dog (6)

Guinea pig (4)

Horse (6)

Monkey (6)

Orangutan (3)

Pig (7)

Rabbit (6)

Sheep (1)

Xenopus (6)

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Application

IHC (18)

IHC-P (5)

WB (41)

ELISA (26)

ICC (2)

IF (14)

IP (10)

Peptide-ELISA (4)

Host

rabbit (46)

mouse (1)

goat (1)

Product Group

IHCPlus (3)

Isotype

IgG (33)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (47)

Clone

4G11 (1)

Format

96-Well Microplate (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (32)

Epitope

aa150-179 (7)

C-Terminus (6)

aa150-200 (2)

670-750 aa, C-terminal (1)

Ile726 (1)

Internal (1)

aa264-280 (1)

aa695-745 (1)

aa696-745 (1)

aa720-745 (1)

aa733-745 (1)

aa748-759 (1)

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Publications

No (53)

Yes (1)

Sample Type

Adherent Cell Cultures (1)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ CUL2 / Cullin 2 Antibody (aa696-745) LS-B7019

(4.0) Rating

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (aa696-745) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ CUL2 / Cullin 2 Antibody (aa720-745) LS-B358

(5.0) Rating

(2) Publication(s)

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (aa720-745) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$515

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IHC-plus™ CUL2 / Cullin 2 Antibody (aa748-759) LS-B8334

(4.0) Rating

Antibody:

CUL2 / Cullin 2 Goat anti-Human Polyclonal (aa748-759) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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CUL2 / Cullin 2 Antibody (C-Terminus) LS-C353051

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Rat, Pig, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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CUL2 / Cullin 2 Antibody LS-C800262

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CUL2 / Cullin 2 Antibody LS-C825920

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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CUL2 / Cullin 2 Antibody LS-C415840

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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CUL2 / Cullin 2 Antibody LS-C664864

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

CUL2 / Cullin 2 Antibody LS-C806590

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CUL2 / Cullin 2 Antibody (670-750 aa, C-terminal) LS-C382947

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (670-750 aa, C-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CUL2 / Cullin 2 Antibody (Ile726) LS-C175982

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (Ile726) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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CUL2 / Cullin 2 Antibody LS-C333972

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Human CUL2 / Cullin 2 Protein (Recombinant GST) (Full Length) - LS-G31160

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

113.4 kDa

Price:

10 µg/$479; 25 µg/$670

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CUL2 / Cullin 2 Antibody LS-C658812

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$386

Select

CUL2 / Cullin 2 Antibody (clone 4G11) LS-C198566

Antibody:

CUL2 / Cullin 2 Mouse anti-Human Monoclonal (4G11) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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CUL2 / Cullin 2 Antibody LS-C500911

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CUL2 / Cullin 2 Antibody LS-C834140

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

CUL2 / Cullin 2 Antibody LS-C341145

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

CUL2 / Cullin 2 Antibody (Internal) LS-C137117

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µl/$332

Select

CUL2 / Cullin 2 Antibody (C-Terminus) LS-C6256

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$914

Select

CUL2 / Cullin 2 Antibody LS-C756568

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CUL2 / Cullin 2 Antibody (aa733-745) LS-C90296

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (aa733-745) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Human, Monkey

Applications:

ELISA, WB

Format:

Unconjugated

Price:

1 mg/$901

Select

CUL2 / Cullin 2 Antibody (aa264-280) LS-C313012

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (aa264-280) Antibody

Reactivity:

Xenopus, Chicken, Sheep, Bovine, Rabbit, Guinea pig, Pig, Horse, Bat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CUL2 / Cullin 2 Antibody (aa150-200) LS-C286120

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (aa150-200) Antibody

Reactivity:

Human

Applications:

IHC, IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

CUL2 / Cullin 2 Antibody (aa150-179) LS-C320686

Antibody:

CUL2 / Cullin 2 Rabbit anti-Human Polyclonal (aa150-179) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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