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Anti-CUL1 / Cullin 1 Antibody (C-Terminus) LS-C6251

Ordering

Wt. Vol. Conc. Price
100 µg - - $495
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CUL1 / Cullin 1 Antibodies

Anti-CUL1 / Cullin 1 Antibody (clone AS97.1) LS-C63155
Mouse Monoclonal [clone AS97.1] (IgG2a) to Human CUL1 / Cullin 1
Human, Monkey, Mouse, Rat, Bovine, Rabbit
Western blot
Unconjugated
Anti-CUL1 / Cullin 1 Antibody (C-Terminus) IHC-plus™ LS-B2448
Mouse Monoclonal (IgG1,k) to Human CUL1 / Cullin 1
Human
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human CUL1 / Cullin 1
Human
Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human CUL1 / Cullin 1
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)

Specificity and Use

CUL1 / Cullin 1 antibody was raised against an 11 amino acid synthetic peptide derived from the extreme C-terminus of the human CUL1 protein. This peptide sequence is identical to Drosophila CUL1 (LIN-19) in 9/11 positions and in 7/11 residues with the CUL1 C. elegans and Dictyostelium discoideum homologs.
C-Terminus
Specific for the 86kD CUL-1 protein and does not cross-react with the related CUL2 protein. Antibody reactivity has been confirmed by Western blotting and immunoprecipitation using both recombinant CUL1 protein and cell lysates. Reacts with human CUL1. Reactivity with other species is possible based on sequence homology but has not been tested.
Suitable for use in ELISA, Western Blot, Immunoprecipitation. ELISA: 0.1-1.0 ug/ml. Western Blot: 1-3 ug/ml. Immunoprecipitation: 5-10 ug.

Packaging

PBS, pH 7.2, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About CUL1 / Cullin 1

Q13616 NM_003592 NP_003583.2

CUL1 Antibody, Cullin 1 Antibody, Cullin-1 Antibody, CUL-1 Antibody

Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

Requested From: United States
Date Requested: 12/4/2016

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