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Anti-CTNNB1 / Beta Catenin Antibody (phospho-Tyr654, clone 1B11) LS-C21356

Ordering

Wt. Vol. Conc. Price
100 µg - - $680
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CTNNB1 / Beta Catenin Antibodies

Anti-CTNNB1 / Beta Catenin Antibody (C-Terminus) LS-C31415
Rabbit Polyclonal (IgG) to Human CTNNB1 / Beta Catenin
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CTNNB1 / Beta Catenin Antibody (clone 4D5) IHC-plus™ LS-B4123
Mouse Monoclonal [clone 4D5] (IgG1) to Human CTNNB1 / Beta Catenin
Human
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CTNNB1 / Beta Catenin Antibody (phospho-Ser552) LS-C381829
Rabbit Polyclonal (IgG) to Human CTNNB1 / Beta Catenin
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 1B11] (IgG1) to Human CTNNB1 / Beta Catenin
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus, Zebrafish, Drosophila
Western blot, ELISA
Unconjugated

Details

Human CTNNB1 / Beta Catenin
Mouse
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus, Zebrafish, Drosophila (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1B11]
Unconjugated
Gel filtration
Unmodified

Applications

  • Western blot (1 µg/ml)
  • ELISA

Specificity and Use

CTNNB1 / Beta Catenin antibody was raised against synthetic peptide corresponding to a portion of beta-catenin phosphorylated at Tyr654. Epitope: phosphotyrosine 654 (VATpYAAA).
pTyr654
Recognizes beta-catenin phosphorylated at Tyr654 and -catenin phosphorylated at Tyr654. Detects bands of ~90kD (beta-catenin) and ~70kD (gamma-catenin). Due to sequence homologies of the phospho-epitope surrounding Tyr654, there may be cross-reactions with other proteins (e. g., Annexin A11 at 56kD, desmoplakin at 81kD, TNF-alpha-induced protein 2 at 73kD, ribosomal protein S6 kinase alpha 6 at 90kD). Species cross-reactivity: human, mouse and canine.
Suitable for use in ELISA and Western Blot. Western Blot: 1 ug/ml (HRP/ECL). Recommended blocking buffer: CPPT (0.5% casein, 1% PEG 4000, 1% Polyvinylpyrrolidone (PVP), 0.1% Tween 20, 2X PBS).

Packaging

PBS, 0.1% sodium azide, G, Sucrose, 40% glycerol.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About CTNNB1 / Beta Catenin

P35222 NM_001904 NP_001895.1

CTNNB1 Antibody, Beta-catenin Antibody, Catenin beta-1 Antibody, CTNNB Antibody, Beta Catenin Antibody

Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.

Requested From: United States
Date Requested: 12/7/2016

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