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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTNNB1 / Beta Catenin Antibody (phospho‑Thr41/Ser45) LS‑C21354
Beta Catenin antibody LS-C21354 is an unconjugated rabbit polyclonal antibody to Beta Catenin (CTNNB1) from human, mouse and monkey. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C21354-100
100 µl
$575

Popular CTNNB1 / Beta Catenin Products

Anti-CTNNB1 / Beta Catenin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4123 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
CTNNB1 / Beta Catenin antibody LS-C31415 was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Dog, Guinea pig, Horse, Rabbit, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Anti-CTNNB1 / Beta Catenin antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1592 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Hamster
Applications: IHC, IHC - Paraffin, Western blot
Western blot of Phospho-Catenin-beta (S552) antibody
Species: Human, Mouse, Rat
Applications: Western blot, ELISA
Western blot analysis of extracts from MCF-7 cells.
Species: Human
Applications: Western blot

Product Description

Beta Catenin antibody LS-C21354 is an unconjugated rabbit polyclonal antibody to Beta Catenin (CTNNB1) from human, mouse and monkey. Validated for ELISA and WB.
About CTNNB1 / Beta Catenin
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. P35222 NM_001904 NP_001895.1

CTNNB1 Antibody, Beta-catenin Antibody, Catenin beta-1 Antibody, CTNNB Antibody, Beta Catenin Antibody


Specifications

Target
Human CTNNB1 / Beta Catenin
Host
Rabbit
Reactivity
Human, Monkey, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • ELISA
Immunogen
Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Thr41 and Ser45 of human beta-catenin.
Epitope
pThr41/Ser45
Specificity
Phospho-beta-Catenin (Thr41/Ser45) Antibody detects endogenous levels of beta-catenin only when phosphorylated at Thr41 or Ser45. This antibody does not recognize beta-catenin phosphorylated at other sites. Species cross-reactivity: Human, mouse and monkey.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/18/2018

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