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Anti-CTNNB1 / Beta Catenin Antibody (aa758-771) IHC-plus™ LS-B3110

Note: This antibody replaces LS-C21242

Ordering

Wt. Vol. Conc. Price
50 µg - 0.3 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CTNNB1 / Beta Catenin Antibodies

Anti-CTNNB1 / Beta Catenin Antibody (C-Terminus) LS-C31415
Rabbit Polyclonal (IgG) to Human CTNNB1 / Beta Catenin
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CTNNB1 / Beta Catenin Antibody (clone 4D5) IHC-plus™ LS-B4123
Mouse Monoclonal [clone 4D5] (IgG1) to Human CTNNB1 / Beta Catenin
Human
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CTNNB1 / Beta Catenin Antibody (phospho-Ser552) LS-C381829
Rabbit Polyclonal (IgG) to Human CTNNB1 / Beta Catenin
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG) to Human CTNNB1 / Beta Catenin
Human
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated

Details

Human CTNNB1 / Beta Catenin
Mouse
Human (tested or 100% immunogen sequence identity)
IgG Monoclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • ICC
  • Western blot
  • Immunoprecipitation

Specificity and Use

CTNNB1 / Beta Catenin antibody was raised against recombinant human beta-catenin (~88kD).
aa758-771
Recognizes an epitope in the carboxy terminus, amino acids 758-771, of human beta-catenin.
Immunohistochemistry: LS-B3110 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3110 was determined to be 10 ug/ml.

Packaging

PBS, pH 7.6. No stabilizing proteins, preservatives, no glycerol added.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CTNNB1 / Beta Catenin

P35222 NM_001904 NP_001895.1

CTNNB1 Antibody, Beta-catenin Antibody, Catenin beta-1 Antibody, CTNNB Antibody, Beta Catenin Antibody

Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.

Immunohistochemistry

Immunohistochemistry
Anti-CTNNB1 / Beta Catenin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3110 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-CTNNB1 / Beta Catenin antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3110 concentration 10 ug/ml.

Requested From: United States
Date Requested: 12/10/2016

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