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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTNNB1 / Beta Catenin Antibody (aa45‑94) LS‑C31417
Antibody
Beta Catenin antibody LS-C31417 is an unconjugated rabbit polyclonal antibody to Beta Catenin (CTNNB1) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C31417-100
100 µg (1 mg/ml)
Unavailable

Popular CTNNB1 / Beta Catenin Products

CTNNB1 / Beta Catenin antibody LS-C31415 was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Dog, Guinea pig, Horse, Rabbit, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Anti-CTNNB1 / Beta Catenin antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1592 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Hamster
Applications: IHC, IHC - Paraffin, Western blot
Anti-CTNNB1 / Beta Catenin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4123 dilution 1:200.
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Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
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Western blot of Phospho-Catenin-beta (S552) antibody
Species: Human, Mouse, Rat
Applications: Western blot, ELISA

Product Description

Beta Catenin antibody LS-C31417 is an unconjugated rabbit polyclonal antibody to Beta Catenin (CTNNB1) from human, mouse, rat and other species. Validated for WB.
About CTNNB1 / Beta Catenin
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. P35222 NM_001904 NP_001895.1

CTNNB1 Antibody, Beta-catenin Antibody, Catenin beta-1 Antibody, CTNNB Antibody, Beta Catenin Antibody


Specifications

Target
Human CTNNB1 / Beta Catenin
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Predicted
Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Protein A/G purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide located between aa45-94 of human CTNNB1 (P35222, NP_001895). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Salmon (100%); Xenopus (92%); Stickleback, Zebrafish (91%).
Blocking Peptide
LS-E10759 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31417. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa45-94
Specificity
Human CTNNB1 / Beta Catenin
Presentation
Lyophilized.
Reconstitution
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/17/2018

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