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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTLA4 / CD152 Antibody (PE) LS‑C14307
CD152 antibody LS-C14307 is a PE-conjugated mouse monoclonal antibody to human CD152 (CTLA4). Validated for Flow.
Antibody
Catalog
Size
Price
LS-C14307-100
100 tst
$845

Popular CTLA4 / CD152 Products

Antibody
Species: Human
Applications: Flow Cytometry
Flow cytometry of CTLA4 / CD152 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA, Functional Assay
Antibody
Species: Human
Applications: Neutralization
Antibody
Species: Human
Applications: Western blot, ELISA
Western blot of recombinant CTLA4 / CD152.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot

Product Description

CD152 antibody LS-C14307 is a PE-conjugated mouse monoclonal antibody to human CD152 (CTLA4). Validated for Flow.

Specifications

Target
Human CTLA4 / CD152
Synonyms
CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Phycoerythrin
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Failed Applications
  • IHC - Paraffin
Immunogen
CTLA4 / CD152 antibody was raised against human CTLA-4/human IgG heavy chain fusion protein.
Specificity
Recognizes human CD152 cell surface antigen, also known as CTLA-4 (Cytolytic T Lymphocyte Associated Antigen 4).
Usage
Suitable for use in Flow Cytometry, Immunohistochemistry with frozen tissues. Flow Cytometry: Use 21 ul of the suggested working dilution to label 1E6 cells in 100ul. Membrane permeabilization may be applicable for studies with this antibody. We recommend the use of a suitable Fixation/Permeabilization medium for this purpose. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 2 mg/ml BSA, 0.1% Sodium Azide
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About CTLA4 / CD152
CTLA4 / CD152 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. P16410 NM_005214 NP_005205.2


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Requested From: United States
Date Requested: 10/16/2018

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