Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone KT56] (IgG1) to Human CTLA4 / CD152
Western blot, ELISA
Mouse Monoclonal [clone WKH203] (IgG1) to Rat CTLA4 / CD152
Rat CTLA4 / CD152
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [WKH203]
Specificity and Use
CTLA4 / CD152 antibody was raised against purified rCTLA-4hlg fusion protein.
Anti-rat CD 152 monoclonal antibody is specific for the cytotoxic T lymphocyte- associated protein 4 (CTLA-4), also called CD 152. This antigen is known to be the receptor for B7 ligands (CD80 and CD86) present on antigen presenting cells. A subset of CD4.
PBS, 0.02% sodium azide.
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
CTLA4 / CD152 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer.