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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTLA4 / CD152 Antibody (clone ANC152.2/8H5, Biotin) LS‑C14301
CD152 antibody LS-C14301 is a biotin-conjugated mouse monoclonal antibody to human CD152 (CTLA4). Validated for Flow and IHC.
Antibody
Catalog
Size
Price
LS-C14301-100
100 µg (1 mg/ml)
$635

Popular CTLA4 / CD152 Products

Antibody
Species: Human
Applications: Flow Cytometry
Flow cytometry of CTLA4 / CD152 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA, Functional Assay
Antibody
Species: Human
Applications: Neutralization
Antibody
Species: Human
Applications: Western blot, ELISA
Western blot of recombinant CTLA4 / CD152.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot

Product Description

CD152 antibody LS-C14301 is a biotin-conjugated mouse monoclonal antibody to human CD152 (CTLA4). Validated for Flow and IHC.

Specifications

Target
Human CTLA4 / CD152
Synonyms
CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [ANC152.2/8H5]
Conjugations
Biotin
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CTLA4 / CD152 antibody was raised against stimulated human PBLs and human CD152 Ig fusion protein.
Specificity
Recognizes human CTLA-4 expressed on activated T cells. Blocks binding of Cd152 (CTLA-4) Ig fusion protein to it CD80/CD86 receptor.
Usage
Suitable for use in Flow Cytometry, ELISA, Immunohistochemistry. Immunohistochemistry: Frozen sections. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl, 0.04% Sodium Azide, 5% Glycerol, 0.2% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CTLA4 / CD152
CTLA4 / CD152 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. P16410 NM_005214 NP_005205.2


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Requested From: United States
Date Requested: 10/22/2018

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