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Anti-CTLA4 / CD152 Antibody (clone 9H10, Azide-free) LS-C14298

Catalog Size Price
LS-C14298-500 500 µg (0.5 mg/ml) Unavailable

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100% Guaranteed
Hamster Monoclonal [clone 9H10] (IgG,k) to Mouse CTLA4 / CD152
Mouse
Immunoprecipitation, Flow Cytometry
Unconjugated, Azide-free

Details

Mouse CTLA4 / CD152
Hamster
Mouse (tested or 100% immunogen sequence identity)
IgG,k Monoclonal [9H10]
Unconjugated
Purified
Azide-free

Applications

  • Immunoprecipitation
  • Flow Cytometry

Specificity and Use

CTLA4 / CD152 antibody was raised against heat-killed Staphylococcus A bacteria coated with mouse CTLA-4/human IgG1 fusion protein.
Recognizes mouse CD152/CTLA-4 costimulatory receptor, Mr 69kD.
Flow cytometry. Immunoprecipitation. In vitro and in vivo blocking of CTLA-4 action by soluble antibody. Promotion of in vitro CTLA-4 signalling by cross-linked antibody. Flow Cytometry: 3 ug/1E6 cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Packaging

100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About CTLA4 / CD152

P16410 NM_005214 NP_005205.2

CTLA4 Antibody, CD152 Antibody, CELIAC3 Antibody, CD152 antigen Antibody, CTLA-4 Antibody, Celiac disease 3 Antibody, IDDM12 Antibody, GRD4 Antibody, GSE Antibody, CD152 isoform Antibody

CTLA4 / CD152 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer.

Requested From: 
Date Requested: 2/25/2018

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