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CTLA4 / CD152
cytotoxic T-lymphocyte-associated protein 4
CTLA4 / CD152 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
| Gene Name: | cytotoxic T-lymphocyte-associated protein 4 |
| Synonyms: | CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform |
| Target Sequences: | NM_005214 NP_005205.2 P16410 |
Publications (6)
1
Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles. Pugholm LH, Bæk R, Søndergaard EK, Revenfeld AL, Jørgensen MM, Varming K. Journal of immunology research. 2016 2016:6391264. (Flo; Human)
[Full Text Article]
[PubMed:27195303]
[PMC:PMC4852366]
Related Antibodies: LS-C134750.
2
Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes. Norström MM, Rådestad E, Sundberg B, Mattsson J, Henningsohn L, Levitsky V, Uhlin M. Oncotarget. 2016 7:23581-93. (Flo, ELISA; Human)
[Full Text Article]
[PubMed:26993768]
[PMC:PMC5029649]
3
The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes. Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG. The Journal of investigative dermatology. 2016 November;136:2173-2182. (Human)
[Full Text Article]
[PubMed:27185339]
Related Antibodies: LS-C35849.
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(200)
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CTLA4 / CD152 Mouse anti-Human Monoclonal (ANC152.2/8H5) Antibody
Human
ELISA, Flo, Func
Unconjugated
100 µg/$446
CTLA4 / CD152 Mouse anti-Human Monoclonal (Biotin) (ANC152.2/8H5) Antibody
Human
ELISA, Flo, Func
Biotin Conjugated
100 µg/$536
CTLA4 / CD152 Rabbit anti-Mouse Polyclonal (aa36-161) Antibody
Mouse, Rat
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CTLA4 / CD152 Mouse anti-Human Monoclonal (Azide-free) (ANC152.2/8H5) Antibody
Human
ELISA, Flo, Func
Unconjugated, Azide-free
100 µg/$446
CTLA4 / CD152 Mouse anti-Human Monoclonal (Fab'2) (ANC152.2/8H5) Antibody
Human
ELISA, Flo, Func
Unconjugated, Fab'2
100 µg/$1,056
CTLA4 / CD152 Mouse anti-Human Monoclonal (KT56) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$437
CTLA4 / CD152 Mouse anti-Human Monoclonal Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$351; 0.5 ml/$491; 1 ml/$754
CTLA4 / CD152 Rabbit anti-Mouse Polyclonal (aa45-185) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
CTLA4 / CD152 Mouse anti-Human Monoclonal (Azide-free) (5D3) Antibody
Human
Flo, ICC
Unconjugated, Azide-free
100 µg/$1,315
CTLA4 / CD152 Mouse anti-Human Monoclonal (KT50) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$454
![CTLA4 / CD152 Antibody - Immunofluorescence of monoclonal antibody to CTLA4 on HeLa cell . [antibody concentration 15 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/ctla4-cd152-antibody-clone-2f1-ls-c196996/144454_4870397.jpg)
CTLA4 / CD152 Mouse anti-Human Monoclonal (2F1) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
CTLA4 / CD152 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
CTLA4 / CD152 Rabbit anti-Human Polyclonal (aa50-78) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
CTLA4 / CD152 Mouse anti-Human Monoclonal (Concentrated) (BNI3) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated, Concentrated
0.2 mg/$920
CTLA4 / CD152 Hamster anti-Mouse Monoclonal (Azide-free) (1B8) Antibody
Mouse
Flo, IP
Unconjugated, Azide-free
500 µg/$685
CTLA4 / CD152 Rabbit anti-Human Recombinant Monoclonal (C-Terminus) (Ready-to-Use) (RBT-CTLA4) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$413; 7 ml/$623; 15 ml/$1,121
CTLA4 / CD152 Rabbit anti-Human Recombinant Monoclonal (C-Terminus) (RBT-CTLA4) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$432; 0.5 ml/$1,121; 1 ml/$2,160
CTLA4 / CD152 Rabbit anti-Human Polyclonal (aa52-211) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
CTLA4 / CD152 Rabbit anti-Dog Polyclonal Antibody
Dog
ELISA
Unconjugated
100 µl/$412
CTLA4 / CD152 Hamster-Armenian anti-Mouse Monoclonal (1B8) Antibody
Mouse
ELISA, Flo, IF, IP, WB
Unconjugated
0.1 mg/$385; 0.25 mg/$471
CTLA4 / CD152 Hamster anti-Mouse Monoclonal (Low Endotoxin) (1B8) Antibody
Mouse
ELISA, Flo, IF, IP, WB
Unconjugated, Low Endotoxin
0.5 mg/$626
Sandwich
96-Well Strip Plate
Dog
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$929
CTLA4 / CD152 Mouse anti-Human Monoclonal (PE) (BNI3) Antibody
Human
Flo, ICC, IHC-Fr, IP
PE Conjugated
100 Tests/$365
CTLA4 / CD152 Mouse anti-Human Monoclonal (Biotin) (ANC152.2/8H5) Antibody
Human
Flo, IHC, IHC-Fr
Biotin Conjugated
100 µg/$763
Viewing 1-25
of 200
product results
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