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CSTB / Cystatin B / Stefin B

cystatin B (stefin B)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

Gene Name: cystatin B (stefin B)
Synonyms: CSTB, CPI-B, EPM1, EPM1A, PME, Stefin B, Stefin-B, ULD, Cystatin b, Cystatin B (stefin B), Cystatin-B, STFB
Target Sequences: NM_000100 NP_000091.1 P04080

☰ Filters
Antibodies (129)
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CSTB / Cystatin B / Stefin B (155)
Human (88)
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CSTB / Cystatin B / Stefin B Antibody - Anti-CSTB / Stefin B antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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CSTB / Cystatin B / Stefin B Goat anti-Human Polyclonal (aa86-98) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CSTB / Cystatin B / Stefin B Antibody - Anti-CSTB / Cystatin B / Stefin B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CSTB / Cystatin B / Stefin B Antibody - Anti-CSTB / Stefin B antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CSTB / Cystatin B / Stefin B Mouse anti-Human Monoclonal (M2F1) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CSTB / Cystatin B / Stefin B Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Stefin B Antibody. The picture on the right is blocked with the synthesized peptide.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (aa49-98) Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CSTB / Cystatin B / Stefin B Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CSTB / Cystatin B / Stefin B Antibody - Western blot of Cystatin-B antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 10 kDa. Observed band size: 10 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
CSTB / Cystatin B / Stefin B Antibody - Anti-CSTB / Stefin B antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CSTB / Cystatin B / Stefin B Mouse anti-Human Monoclonal (M1-C1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CSTB / Cystatin B / Stefin B Antibody - CSTB / Stefin B antibody CSTB(cystatin B (stefin B)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
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CSTB / Cystatin B / Stefin B Mouse anti-Human Monoclonal (aa1-99) (Azide-free) Antibody
Human
ELISA, WB
Unconjugated, Azide-free
100 µg/$705
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$331
CSTB / Cystatin B / Stefin B Antibody - Immunohistochemical analysis of Cystatin B staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
CSTB / Cystatin B / Stefin B Antibody - 1:100 staining human lung carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CSTB / Cystatin B / Stefin B Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stefin B antibody.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
CSTB / Cystatin B / Stefin B Antibody - Western blot of A549 cell lysate using CSTB Antibody
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal Antibody
Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
CSTB / Cystatin B / Stefin B Antibody - IHC analysis of Stefin B using anti-Stefin B antibody. Stefin B was detected in paraffin-embedded section of human tonsil tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml mouse anti-Stefin B Antibody overnight at 4°C. Biotinylated goat anti-mouse IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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CSTB / Cystatin B / Stefin B Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CSTB / Cystatin B / Stefin B Antibody - Western blot of Cystatin B antibody
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (20-100 aa, Internal) Antibody
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CSTB / Cystatin B / Stefin B Antibody - Stefin B antibody IHC-paraffin. IHC(P): Human Prostatic Cancer Tissue.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (aa1-98) Antibody
Dog, Sheep, Bovine, Rat, Pig, Horse, Bat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CSTB / Cystatin B / Stefin B Antibody - IHC of Stefin B (N84) pAb in paraffin-embedded human breast carcinoma tissue.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (Asn84) Antibody
Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
CSTB / Cystatin B / Stefin B Protein - Recombinant Cystatin B By SDS-PAGE
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E. coli
His
12.4 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
CSTB / Cystatin B / Stefin B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CSTB / Cystatin B / Stefin B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CSTB / Cystatin B / Stefin B Antibody
Select
CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$575
CSTB / Cystatin B / Stefin B Antibody - CSTB / Cystatin B / Stefin B antibody. IHC(P): Human Lung Cancer Tissue.
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CSTB / Cystatin B / Stefin B Rabbit anti-Human Polyclonal (aa26-45) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CSTB / Cystatin B / Stefin B Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-CSTB mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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CSTB / Cystatin B / Stefin B Mouse anti-Human Monoclonal (aa1-98) (OTI5F2) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
CSTB / Cystatin B / Stefin B Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-CSTB mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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CSTB / Cystatin B / Stefin B Mouse anti-Human Monoclonal (aa1-98) (Carrier-free) (OTI5F2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Viewing 1-25 of 155 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).