CSNK1D

casein kinase 1, delta

Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, determines the circadian period length through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. YAP1 phosphorylation promotes its SCF(beta-TRCP) E3 ubiquitin ligase-mediated ubiquitination and subsequent degradation. DNMT1 phosphorylation reduces its DNA-binding activity. Phosphorylation of ESR1 and AIB1/NCOA3 stimulates their activity and coactivation. Phosphorylation of DVL2 and DVL3 regulates WNT3A signaling pathway that controls neurite outgrowth. EIF6 phosphorylation promotes its nuclear export. Triggers down-regulation of dopamine receptors in the forebrain. Activates DCK in vitro by phosphorylation. TOP2A phosphorylation favors DNA cleavable complex formation. May regulate the formation of the mitotic spindle apparatus in extravillous trophoblast. Modulates connexin-43/GJA1 gap junction assembly by phosphorylation. Probably involved in lymphocyte physiology. Regulates fast synaptic transmission mediated by glutamate.

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Products

Antibodies (42)

Proteins (8)

ELISA Kits (1)

Type

Over-Expression Lysate (4)

Primary (42)

Recombinant (4)

Sandwich (1)

Target

CSNK1D (51)

Reactivity

Human (36)

Mouse (19)

Rat (12)

Bat (4)

Bovine (5)

Chicken (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Hamster (1)

Horse (4)

Monkey (5)

Orangutan (3)

Pig (4)

Rabbit (4)

Xenopus (3)

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Application

IHC (13)

IHC-P (3)

WB (37)

ELISA (21)

IF (2)

IP (2)

Peptide-ELISA (3)

Host

rabbit (39)

mouse (1)

goat (1)

sheep (1)

Isotype

IgG (28)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (41)

Clone

4H8 (1)

Format

96-Well Strip Plate (1)

APC (1)

APC Conjugated (3)

Azide-free (2)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Unconjugated (19)

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Epitope

aa1-415 (8)

aa204-231 (7)

aa321-352 (7)

aa143-192 (4)

260-340 aa, Internal (1)

Internal (1)

aa291-340 (1)

aa310-324 (1)

aa334-379 (1)

aa359-409 (1)

Publications

No (51)

Sample Type

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Select

CSNK1D Antibody (clone 4H8) LS-C133872

Antibody:

CSNK1D Mouse anti-Human Monoclonal (4H8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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Human CSNK1D Protein (Recombinant His) - LS-G2905

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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CSNK1D Antibody (aa310-324) LS-C54610

Antibody:

CSNK1D Goat anti-Human Polyclonal (aa310-324) Antibody

Reactivity:

Mouse, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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CSNK1D Antibody (aa1-415) LS-C373134

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa1-415) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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CSNK1D Antibody LS-C661673

Antibody:

CSNK1D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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CSNK1D Antibody LS-C375538

Antibody:

CSNK1D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CSNK1D Antibody (HRP) LS-C375541

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CSNK1D Antibody (Biotin) LS-C375540

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

CSNK1D Antibody (FITC) LS-C375537

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CSNK1D Antibody (aa321-352) LS-C327017

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa321-352) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CSNK1D Antibody (aa321-352, Biotin) LS-C275937

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa321-352) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CSNK1D Antibody (aa321-352, FITC) LS-C275938

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa321-352) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

CSNK1D Antibody (aa321-352, APC) LS-C275936

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa321-352) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

CSNK1D Antibody (aa321-352, Azide-free, HRP) LS-C275939

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa321-352) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

CSNK1D Antibody (aa321-352, PE) LS-C275940

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa321-352) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

CSNK1D Antibody (aa321-352) LS-C100598

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (aa321-352) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

CSNK1D Antibody (aa204-231) LS-C320638

Antibody:

CSNK1D Rabbit anti-Mouse Polyclonal (aa204-231) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CSNK1D Antibody (aa204-231, Biotin) LS-C255543

Antibody:

CSNK1D Rabbit anti-Mouse Polyclonal (aa204-231) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CSNK1D Antibody (aa204-231, FITC) LS-C255544

Antibody:

CSNK1D Rabbit anti-Mouse Polyclonal (aa204-231) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

CSNK1D Antibody (aa204-231, APC) LS-C255542

Antibody:

CSNK1D Rabbit anti-Mouse Polyclonal (aa204-231) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

CSNK1D Antibody (aa204-231, PE) LS-C255545

Antibody:

CSNK1D Rabbit anti-Mouse Polyclonal (aa204-231) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

CSNK1D Antibody (aa204-231, Azide-free, HRP) LS-C255546

Antibody:

CSNK1D Rabbit anti-Mouse Polyclonal (aa204-231) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

CSNK1D Antibody LS-C401553

Antibody:

CSNK1D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CSNK1D Antibody LS-C824906

Antibody:

CSNK1D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CSNK1D Antibody (260-340 aa, Internal) LS-C382443

Antibody:

CSNK1D Rabbit anti-Human Polyclonal (260-340 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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