Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1 - 10 µg/ml)
Specificity and Use
CSF3R / CD114 antibody was raised against purified recombinant MBP-GCSFR fusion protein.
Recognizes human G-CSFR. Does not cross-react with MBP or BSA.
Suitable for use in ELISA, Western Blot and Western Blot. Western Blot: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 ug of cell lysate or following immunoprecipitation with polyclonal antibody followed by immunoblotting. Western Blot: 1-10 ug/ml will allow visualization of 250 ng/lane of human G-CSFR-MBP.
PBS, pH 7.2, 40% glycerol.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C.
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.