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CSE1L

CSE1 chromosome segregation 1-like (yeast)

Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

Gene Name: CSE1 chromosome segregation 1-like (yeast)
Synonyms: CSE1L, CAS, CSE1, Exp2, Importin-alpha re-exporter, Exportin-2, XPO2
Target Sequences: NM_001316 NP_001307.2 P55060

Publications (1)

1
Higher prevalence of secretory CSE1L/CAS in sera of patients with metastatic cancer. Tung MC, Tsai CS, Tung JN, Tsao TY, Chen HC, Yeh KT, Liao CF, Jiang MC. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2009 18:1570-7. [PubMed:19383891]

☰ Filters
Antibodies (25)
Proteins (6)
ELISA Kits (2)
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Over-Expression Lysate (2)
Primary (25)
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CSE1L (33)
Human (27)
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rabbit (17)
mouse (8)
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monoclonal mc (8)
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CSE1L Antibody - Anti-CSE1L antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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CSE1L Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IF, IHC, IHC-P, IP, Peptide-ELISA, WB
Unconjugated
50 µl/$460
CSE1L Antibody - Immunofluorescence of monoclonal antibody to CSE1L on HeLa cell (antibody concentration 10 ug/ml).
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CSE1L Mouse anti-Human Monoclonal (2C10) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
CSE1L Antibody - Anti-CSE1L antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CSE1L Mouse anti-Human Monoclonal (3F8) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CSE1L Antibody - Anti-CSE1L antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CSE1L Mouse anti-Human Monoclonal (2F4) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CSE1L Antibody - Detection of Human CSE1 by Immunohistochemistry. Sample: FFPE section of human breast tumor. Antibody: Affinity purified rabbit anti-CSE used at a dilution of 1:500.
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CSE1L Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC
Unconjugated
1 µg/$295; 100 µl/$532
CSE1L Antibody - Immunohistochemical analysis of XPO2 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CSE1L Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Bovine, Mouse, Dog, Rat, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
CSE1L Antibody - IHC of paraffin-embedded Cal27 Xenograft using CSE1L antibody at 1:500 dilution.
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CSE1L Rabbit anti-Human Polyclonal (aa222-469) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
CSE1L Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using CSE1 antibody.
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CSE1L Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
CSE1L Antibody - Western blot of CAS antibody
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CSE1L Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CSE1L Antibody - IHC of CSE1L/Exportin-2 (E2) pAb in paraffin-embedded human brain tissue.
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CSE1L Rabbit anti-Human Polyclonal (Glu2) Antibody
Human
IF, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$321; 100 µl/$403
CSE1L Antibody - Immunofluorescence of monoclonal antibody to CSE1L on HeLa cell (antibody concentration 10 ug/ml).
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CSE1L Mouse anti-Human Monoclonal (3D8) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
CSE1L Antibody - Immunohistochemical staining of paraffin-embedded Human Gastric Carcinoma using anti-CSE1L mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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CSE1L Mouse anti-Human Monoclonal (aa1-300) (OTI4G1) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
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CSE1L Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
CSE1L Antibody - Detection of Human and Mouse CSE1 by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti-CSE1 used at a dilution of 1:5000 (0.2 ug/ml) and 1:1000 (1 ug/ml). Detection: DAB.
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CSE1L Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CSE1L Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CSE1L Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CSE1L Rabbit anti-Human Polyclonal (aa900-950) Antibody
Mouse, Human
IP, WB
Unconjugated
100 µl/$514
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CSE1L Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$786
CSE1L Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY CSE1L. (Right lane) cDNA for 48 hrs and lysed
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CSE1L Mouse anti-Human Monoclonal (aa1-300) (OTI2C5) Antibody
Human
WB
Unconjugated
100 µl/$434
CSE1L Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY CSE1L. (Right lane) cDNA for 48 hrs and lysed
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CSE1L Mouse anti-Human Monoclonal (aa1-300) (OTI5H9) Antibody
Human
WB
Unconjugated
100 µl/$434
CSE1L Antibody - CSE1L antibody Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSE1L Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CSE1L Antibody - CSE1L antibody Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSE1L Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$469
CSE1L Antibody - CSE1L antibody Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSE1L Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
CSE1L Antibody - CSE1L antibody Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSE1L Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$469
CSE1L Antibody - All lanes : Anti-XPO2 Antibody at 1:1000 dilution Lane 1: K562 whole cell lysates Lane 2: MCF-7 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 110 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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CSE1L Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
CSE1L Antibody - Western blot analysis of extracts of various cell lines.
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CSE1L Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 33 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).