Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Bovine (tested or 100% immunogen sequence identity)
Protein G purified
Specificity and Use
CRYBA1 antibody was raised against bovine betaH-crystallin.
Detects a ~25kD protein, corresponding to the apparent molecular mass of beta-crystallin on SDS-PAGE immunoblots, in samples from bovine. There may be weak reactivity with alphaA crystallin detected on immunoblot analysis.
Western Blot (Colorimetric): 1 ug/mL. Positive control: Bovine beta-Crystallin Protein.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins.