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Anti-CRLF2 / TSLPR Antibody (aa30-232) LS-C150093

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CRLF2 / TSLPR Antibodies

Anti-CRLF2 / TSLPR Antibody (CF) LS-C76383
Goat Polyclonal (IgG) to Mouse CRLF2 / TSLPR
Mouse
Flow Cytometry
CF Conjugated
Flow Cytometry Image
Anti-CRLF2 / TSLPR Antibody (Internal) IHC-plus™ LS-B3211
Rabbit Polyclonal (IgG) to Human CRLF2 / TSLPR
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CRLF2 / TSLPR Antibody (clone 8H8) IHC-plus™ LS-B6755
Mouse Monoclonal [clone 8H8] (IgG1,k) to Human CRLF2 / TSLPR
Human
IHC - Paraffin, ICC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human CRLF2 / TSLPR
Human
IHC - Paraffin, ICC, Western blot, Neutralization
Unconjugated

Details

Human CRLF2 / TSLPR
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 - 15 µg/ml)
  • ICC (5 - 15 µg/ml)
  • Western blot (1 µg/ml)
  • Neutralization

Specificity and Use

CRLF2 / TSLPR antibody was raised against mouse myeloma cell line NS0-derived recombinant human TSLP R Val30-Phe232 Accession # Q9HC73.
aa30-232
Detects human TSLP R in direct ELISAs and Western blots.
Western Blot, 1 µg/ml. Immunocytochemistry, 5-15 µg/ml, Immersion fixed human peripheral blood mononuclear cells (PBMCs). Immunohistochemistry, 5-15 µg/ml. Neutralization, Measured by its ability to neutralize TSLP-induced proliferation in the BaF3 mouse pro-B cell line co-transfected. With human IL-7 R alpha and TSLP R. The Neutralization Dose (ND50) is typically 1-5 µg/ml in the presence of 0.3 ng/ml Recombinant Human TSLP.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 500 ul
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About CRLF2 / TSLPR

Q9HC73 AK026800 BAB15557.1

CRLF2 Antibody, IL-XR Antibody, ILXR Antibody, p2RY8/CRLF2 fusion Antibody, TSLP receptor Antibody, TSLPR Antibody, CRL2 Antibody, CRLF2Y Antibody, Cytokine receptor-like 2 Antibody

CRLF2 / TSLPR is a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system.

Immunohistochemistry

Immunohistochemistry
TSLP R in Human Liver. TSLP R was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human TSLP R Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Western blot

Western blot
TSLP R in Human Liver. TSLP R was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human TSLP R Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Neutralization

Neutralization
Cell Proliferation Induced by TSLP and Neutralization by Human TSLP R Antibody. Recombinant Human TSLP stimulates proliferation in the BaF3 mouse pro-B cell line co-transfected with human IL-7 R alpha and TSLP R in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human TSLP (0.3 ng/ml) is neutralized (green line) by increasing concentrations of Goat Anti-Human TSLP R Antigen Affinity-purified Polyclonal Antibody. The ND50 is typically 1-5 ug/ml.
 

Requested From: United States
Date Requested: 12/11/2016

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