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CRKL

v-crk avian sarcoma virus CT10 oncogene homolog-like

CRKL is a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Gene Name: v-crk avian sarcoma virus CT10 oncogene homolog-like
Synonyms: CRKL, Crk-like protein
Target Sequences: NM_005207 NP_005198.1 P46109

Publications (1)

1
A mouse splice-site mutant and individuals with atypical chromosome 22q11.2 deletions demonstrate the crucial role for crkl in craniofacial and pharyngeal development. Miller KA, Tan TY, Welfare MF, White SM, Stark Z, Savarirayan R, Burgess T, Heggie AA, Caruana G, Bertram JF, Bateman JF, Farlie PG. Molecular syndromology. 2014 5:276-86. (WB; Human) [PubMed:25565927] Related Antibodies: LS-C14694.

☰ Filters
Antibodies (64)
Proteins (9)
ELISA Kits (5)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Over-Expression Lysate (2)
Primary (64)
Recombinant (7)
Sandwich (3)
CRKL (78)
Human (61)
Mouse (27)
Rat (15)
Bat (2)
Chicken (2)
Chimpanzee (3)
Monkey (4)
Pig (8)
IHC (19)
IHC-P (6)
WB (61)
Flo (4)
ELISA (26)
ICC (1)
IF (11)
IP (2)
Peptide-ELISA (3)
RNAi (1)
rabbit (54)
mouse (8)
goat (2)
Product Group
IHCPlus (1)
IgG (36)
IgG1 (5)
IgG2b (1)
IgG2b,k (1)
monoclonal mc (7)
polyclonal pc (57)
1D4B (1)
4B5 (1)
5E+12 (2)
96-Well Microplate (3)
96-Well Strip Plate (2)
APC (1)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (36)
aa1-303 (10)
aa275-303 (7)
aa50-79 (7)
pTyr207 (6)
aa183-232 (4)
150-230 aa (2)
C-Terminus (1)
N-Terminus (1)
Pro201 (1)
aa173-222 (1)
aa286-303 (1)
aa292-303 (1)
p207 (1)
No (77)
Yes (1)
Adherent Cell Cultures (2)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (1)
Serum (1)
Tissue Homogenates (2)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (8)
293T Cells (1)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
CRKL Antibody - Anti-CRKL antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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CRKL Goat anti-Human Polyclonal (aa292-303) Antibody
Chicken, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CRKL ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.205 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
CRKL Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CrkL Antibody. The picture on the right is blocked with the synthesized peptide.
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CRKL Rabbit anti-Human Polyclonal (aa173-222) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
CRKL Mouse anti-Human Monoclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$665
CRKL Antibody - Immunofluorescence of monoclonal antibody to CRKL on HeLa cell . [antibody concentration 10 ug/ml]
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CRKL Mouse anti-Human Monoclonal (4B5) Antibody
Human
ELISA, IF, RNAi, WB
Unconjugated
100 µg/$423
CRKL Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CrkL (Phospho-Tyr207) Antibody. The picture on the right is blocked with the phospho peptide.
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CRKL Rabbit anti-Human Polyclonal (pTyr207) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CRKL Antibody - Western Blot (WB) analysis using Crk-L Monoclonal Antibody against human Crk-L (AA: 100-303) recombinant protein.
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CRKL Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Select
CRKL Rabbit anti-Human Polyclonal (aa50-79) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
CRKL Antibody - Immunohistochemical analysis of CRKL staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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CRKL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
CRKL Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using CrkL (Ab-207) antibody.
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CRKL Rabbit anti-Human Polyclonal (p207) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
CRKL Antibody - P-peptide - + Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using CrkL (phospho-Tyr207) antibody.
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CRKL Rabbit anti-Human Polyclonal (pTyr207) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
CRKL Antibody - Western blot of Crk-L antibody
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CRKL Rabbit anti-Human Polyclonal (150-230 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CRKL Antibody - Western blot of Phospho-Crk-L (Y207) antibody
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CRKL Rabbit anti-Human Polyclonal (150-230 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
CRKL Rabbit anti-Human Polyclonal (pTyr207) Antibody
Human
Flo, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$717
CRKL Antibody - IHC of CrkL (P201) pAb in paraffin-embedded human lung carcinoma tissue.
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CRKL Rabbit anti-Human Polyclonal (Pro201) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
CRKL ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
CRKL Antibody - Immunofluorescent analysis of Hela cells using CRKL Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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CRKL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
CRKL Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using CRKL Polyclonal Antibody at dilution of 1:25.
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CRKL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CRKL Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using CRKL Polyclonal Antibody at dilution of 1:25.
Select
CRKL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CRKL Antibody - Immunohistochemistry (IHC) analysis of p-Crk-L (Y207) pAb in paraffin-embedded human colon cancer tissue.
Select
CRKL Rabbit anti-Human Polyclonal (pTyr207) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$328; 100 µl/$419
Select
CRKL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$489
CRKL Antibody - Western blot using CRKL monoclonal antibody against human CRKL (AA: 100-303) recombinant protein. (Expected MW is 60 kDa)
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CRKL Mouse anti-Human Monoclonal (5E+12) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
CRKL Antibody - CrkL Antibody in Western Blot (WB)
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CRKL Mouse anti-Human Monoclonal (5E+12) Antibody
Mouse, Human
Flo, WB
Unconjugated
100 µl/$518
Select
CRKL Rabbit anti-Mouse Polyclonal (aa275-303) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
CRKL Antibody - CRKL antibody Immunohistochemistry of Human Lung cell. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CRKL Rabbit anti-Human Polyclonal (aa183-232) Antibody
Human
IHC, WB
Unconjugated
100 µl/$424
Viewing 1-25 of 78 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).