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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CRFR1 / CRHR1 Antibody (His177) LS‑C177081
CRHR1 antibody LS-C177081 is an unconjugated rabbit polyclonal antibody to CRHR1 (CRFR1) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C177081-100
100 µl
Unavailable

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Product Description

CRHR1 antibody LS-C177081 is an unconjugated rabbit polyclonal antibody to CRHR1 (CRFR1) from human, mouse and rat. Validated for WB.
About CRFR1 / CRHR1
G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. P34998 NM_004382 P34998

CRHR1 Antibody, CRF-R-1 Antibody, CRFR Antibody, CRHR1f Antibody, Crf receptor 1 Antibody, CRH-R1 Antibody, CRF-R Antibody, CRF1 Antibody, CRFR-1 Antibody, Crf receptor type 1 Antibody, Crf receptor type 1 Antibody, Crf type 1 Antibody, CRF-R1 Antibody, Crf1 receptor Antibody, CRFR1 Antibody, CRH-R-1 Antibody, CRH-R1h Antibody, CRHR Antibody, CRHR1L Antibody


Specifications

Target
Human CRFR1 / CRHR1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
CRFR1 / CRHR1 antibody was raised against synthetic peptide around His177 of human CRFR1 / CRHR1
Epitope
His177
Specificity
Human CRFR1 / CRHR1
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.
Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.

Western blot

Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.
Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.

Western blot

Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.
Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.

Western blot

Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.
Western blot of CRF-RI (H177) pAb in extracts from HT-29 cells.


Requested From: 
Date Requested: 6/23/2018

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