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Anti-CRFR1 / CRHR1 Antibody (Extracellular Domain) IHC-plus™ LS-A6612

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml Unavailable
Same day shipping In Stock - Same day shipping

Most Popular CRFR1 / CRHR1 Antibodies

Anti-CRFR1 / CRHR1 Antibody (N-Terminus) IHC-plus™ LS-A1778
Rabbit Polyclonal to Human CRFR1 / CRHR1
Human, Rat
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-CRFR1 / CRHR1 Antibody (N-Terminus) IHC-plus™ LS-A1779
Rabbit Polyclonal to Human CRFR1 / CRHR1
Human, Monkey, Rat
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-CRFR1 / CRHR1 Antibody (N-Terminus) IHC-plus™ LS-A6603
Rabbit Polyclonal to Human CRFR1 / CRHR1
Human, Monkey, Mouse, Rat, Dog, Hamster, Horse
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed In Stock In Stock
Rabbit Polyclonal to Human CRFR1 / CRHR1
Human, Monkey, Bovine, Dog, Hamster, Horse, Pig, Sheep
IHC - Paraffin
Unconjugated

Details

Human CRFR1 / CRHR1
Rabbit
Human, Monkey, Bovine, Dog, Hamster, Horse, Pig, Sheep (tested or 100% immunogen sequence identity)
Bat (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (20 µg/ml)

Specificity and Use

CRFR1 / CRHR1 antibody was raised against synthetic 18 amino acid peptide from 1st extracellular domain of human CRF1. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Sheep, Hamster, Dog, Bovine, Horse, Pig, Opossum (100%); Elephant, Panda, Bat (94%); Marmoset, Mouse, Rat, Seabass, Stickleback, Pufferfish (89%); Turkey, Chicken, Lizard, Zebrafish (83%).
LS-E29151 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A6612. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Extracellular Domain
Human CRF1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About CRFR1 / CRHR1

P34998 NM_004382 P34998

CRHR1 Antibody, CRF-R-1 Antibody, CRFR Antibody, CRHR1f Antibody, Crf receptor 1 Antibody, CRH-R1 Antibody, CRF-R Antibody, CRF1 Antibody, CRFR-1 Antibody, Crf receptor type 1 Antibody, Crf receptor type 1 Antibody, Crf type 1 Antibody, CRF-R1 Antibody, Crf1 receptor Antibody, CRFR1 Antibody, CRH-R-1 Antibody, CRH-R1h Antibody, CRHR Antibody, CRHR1L Antibody

G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H.

Immunohistochemistry

Immunohistochemistry
Anti-CRFR1 / CRHR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CRF1 antibody LS-A6612 IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CRFR1 / CRHR1 antibody IHC of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CRFR1 / CRHR1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CRFR1 / CRHR1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: 
Date Requested: 3/26/2017

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